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This orthogroup contains 853 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 853 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF02221 | E1_DerP2_DerF2 — ML domain | 765 / 853 | 89.7% | 100.0% of 765 | ≥80% support |
| PANTHER | PTHR11306 | NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED | 675 / 853 | 79.1% | 99.7% of 677 | ≥50% support |
| GO | GO:0015918 Biological Process | sterol transport | 675 / 853 | 79.1% | 99.7% of 677 | ≥50% support |
| GO | GO:0032934 Molecular Function | sterol binding | 675 / 853 | 79.1% | 99.7% of 677 | ≥50% support |
| KEGG | K13443 | NPC2 — Transporters | 526 / 853 | 61.7% | 99.8% of 527 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000012106.1 | KAI0212728.1 | NPC intracellular cholesterol transporter 2 [Lamellibrachia satsuma] | Q9DGJ3 NPC intracellular cholesterol transporter 2 OS=Danio rerio O | JBrowse |
| Catostylus mosaicus | ENSSJYP00000012108.1 | XP_019626026.1 | PREDICTED: epididymal secretory protein E1-like [Branchiostoma belcheri] | Q9DGJ3 NPC intracellular cholesterol transporter 2 OS=Danio rerio O | JBrowse |
| Catostylus mosaicus | ENSSJYP00000015895.1 | KAI4488396.1 | hypothetical protein M0804_005244 [Polistes exclamans] | P79345 NPC intracellular cholesterol transporter 2 OS=Bos taurus OX | JBrowse |
