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This orthogroup contains 367 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 367 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12845 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | 296 / 367 | 80.7% | 99.7% of 297 | ≥80% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 296 / 367 | 80.7% | 99.7% of 297 | ≥80% support |
| GO | GO:0090630 Biological Process | activation of GTPase activity | 296 / 367 | 80.7% | 99.7% of 297 | ≥80% support |
| Pfam | PF00621 | RhoGEF | 279 / 367 | 76.0% | 95.9% of 291 | ≥50% support |
| Pfam | PF00018 | SH3_1 — SH3 domain | 208 / 367 | 56.7% | 71.5% of 291 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 246 / 367 | 67.0% | 82.8% of 297 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000019433.1 | XP_047139246.1 | rho guanine nucleotide exchange factor 16 isoform X6 [Hydra vulgaris] | Q5BKC9 Ephexin-1 OS=Rattus norvegicus OX=10116 GN=Ngef PE=1 SV=2 | JBrowse |
