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This orthogroup contains 341 genes from 137 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 341 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR22870 | REGULATOR OF CHROMOSOME CONDENSATION | 234 / 341 | 68.6% | 87.3% of 268 | ≥50% support |
| Pfam | PF00415 | RCC1 | 242 / 341 | 71.0% | 88.3% of 274 | ≥50% support |
| Pfam | PF00632 | HECT | 187 / 341 | 54.8% | 68.3% of 274 | ≥50% support |
| Pfam | PF06701 | MIB_HERC2 | 179 / 341 | 52.5% | 65.3% of 274 | ≥50% support |
| GO | GO:0004842 Molecular Function | ubiquitin-protein transferase activity | 224 / 341 | 65.7% | 93.3% of 240 | ≥50% support |
| GO | GO:0016567 Biological Process | protein ubiquitination | 181 / 341 | 53.1% | 75.4% of 240 | ≥50% support |
| GO | GO:0046872 Molecular Function | metal ion binding | 181 / 341 | 53.1% | 75.4% of 240 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000023057.1 | XP_045606668.1 | E3 ubiquitin-protein ligase HERC2-like isoform X4 [Procambarus clarkii] | O95714 E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens OX=9606 GN | JBrowse |
| Catostylus mosaicus | ENSSJYP00000023067.1 | XP_028518800.1 | E3 ubiquitin-protein ligase HERC2 [Exaiptasia diaphana] | Q4U2R1 E3 ubiquitin-protein ligase HERC2 OS=Mus musculus OX=10090 G | JBrowse |
| Catostylus mosaicus | ENSSJYP00000023079.1 | EDO37196.1 | predicted protein [Nematostella vectensis] | O95714 E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens OX=9606 GN | JBrowse |
| Catostylus mosaicus | ENSSJYP00000023172.1 | none | – | JBrowse |