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This orthogroup contains 338 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 338 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| GO | GO:0005515 Molecular Function | protein binding | 298 / 338 | 88.2% | 97.7% of 305 | ≥80% support |
| PANTHER | PTHR23119 | DISCS LARGE | 234 / 338 | 69.2% | 86.7% of 270 | ≥50% support |
| Pfam | PF00625 | Guanylate_kin — Guanylate kinase | 240 / 338 | 71.0% | 78.7% of 305 | ≥50% support |
| Pfam | PF00595 | PDZ | 233 / 338 | 68.9% | 76.4% of 305 | ≥50% support |
| Pfam | PF00018 | SH3_1 — SH3 domain | 187 / 338 | 55.3% | 61.3% of 305 | ≥50% support |
| Pfam | PF09058 | L27_1 | 177 / 338 | 52.4% | 58.0% of 305 | ≥50% support |
| GO | GO:0045197 Biological Process | establishment or maintenance of epithelial cell apical/basal polarity | 234 / 338 | 69.2% | 76.7% of 305 | ≥50% support |
| GO | GO:0098609 Biological Process | cell-cell adhesion | 234 / 338 | 69.2% | 76.7% of 305 | ≥50% support |
| GO | GO:0097120 Biological Process | receptor localization to synapse | 234 / 338 | 69.2% | 76.7% of 305 | ≥50% support |
| GO | GO:0043113 Biological Process | receptor clustering | 234 / 338 | 69.2% | 76.7% of 305 | ≥50% support |
| GO | GO:0030054 Cellular Component | cell junction | 234 / 338 | 69.2% | 76.7% of 305 | ≥50% support |
| GO | GO:0016323 Cellular Component | basolateral plasma membrane | 234 / 338 | 69.2% | 76.7% of 305 | ≥50% support |
| GO | GO:0009790 Biological Process | embryo development | 234 / 338 | 69.2% | 76.7% of 305 | ≥50% support |
| GO | GO:0043005 Cellular Component | neuron projection | 219 / 338 | 64.8% | 71.8% of 305 | ≥50% support |
| GO | GO:0031594 Cellular Component | neuromuscular junction | 219 / 338 | 64.8% | 71.8% of 305 | ≥50% support |
| GO | GO:0007268 Biological Process | chemical synaptic transmission | 219 / 338 | 64.8% | 71.8% of 305 | ≥50% support |
| GO | GO:0098839 Cellular Component | postsynaptic density membrane | 217 / 338 | 64.2% | 71.2% of 305 | ≥50% support |
| GO | GO:0019900 Molecular Function | kinase binding | 181 / 338 | 53.6% | 59.3% of 305 | ≥50% support |
| KEGG | K12076 | DLG1 — Chromosome and associated proteins | 217 / 338 | 64.2% | 98.6% of 220 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000020427.1 | CAG7732539.1 | unnamed protein product [Allacma fusca] | P31007 Disks large 1 tumor suppressor protein OS=Drosophila melanog | JBrowse |
| Catostylus mosaicus | ENSSJYP00000020441.1 | XP_047130138.1 | disks large homolog 1 [Hydra vulgaris] | A0A8C0TYJ0 Disks large homolog 1 OS=Canis lupus familiaris OX=9615 GN=D | JBrowse |
| Catostylus mosaicus | ENSSJYP00000020452.1 | XP_020892828.1 | disks large homolog 1 isoform X2 [Exaiptasia diaphana] | A0A8C0TYJ0 Disks large homolog 1 OS=Canis lupus familiaris OX=9615 GN=D | JBrowse |
