← Back to the gene family browser
This orthogroup contains 312 genes from 134 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 312 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45674 | DNA LIGASE 1/3 FAMILY MEMBER | 268 / 312 | 85.9% | 100.0% of 268 | ≥80% support |
| GO | GO:0003910 Molecular Function | DNA ligase (ATP) activity | 271 / 312 | 86.9% | 99.3% of 273 | ≥80% support |
| GO | GO:0006281 Biological Process | DNA repair | 271 / 312 | 86.9% | 99.3% of 273 | ≥80% support |
| GO | GO:0006310 Biological Process | DNA recombination | 271 / 312 | 86.9% | 99.3% of 273 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 268 / 312 | 85.9% | 98.2% of 273 | ≥80% support |
| GO | GO:0006266 Biological Process | DNA ligation | 268 / 312 | 85.9% | 98.2% of 273 | ≥80% support |
| GO | GO:0006273 Biological Process | lagging strand elongation | 268 / 312 | 85.9% | 98.2% of 273 | ≥80% support |
| GO | GO:0006288 Biological Process | base-excision repair, DNA ligation | 268 / 312 | 85.9% | 98.2% of 273 | ≥80% support |
| GO | GO:0006302 Biological Process | double-strand break repair | 268 / 312 | 85.9% | 98.2% of 273 | ≥80% support |
| GO | GO:0070421 Cellular Component | DNA ligase III-XRCC1 complex | 268 / 312 | 85.9% | 98.2% of 273 | ≥80% support |
| Pfam | PF01068 | DNA_ligase_A_M — ATP dependent DNA ligase domain | 244 / 312 | 78.2% | 87.1% of 280 | ≥50% support |
| Pfam | PF04675 | DNA_ligase_A_N — DNA ligase N terminus | 237 / 312 | 76.0% | 84.6% of 280 | ≥50% support |
| Pfam | PF04679 | DNA_ligase_A_C — ATP dependent DNA ligase C terminal region | 224 / 312 | 71.8% | 80.0% of 280 | ≥50% support |
| Pfam | PF16759 | LIG3_BRCT — DNA ligase 3 BRCT domain | 189 / 312 | 60.6% | 67.5% of 280 | ≥50% support |
| Pfam | PF10283 | zf-CCHH — PBZ domain | 189 / 312 | 60.6% | 67.5% of 280 | ≥50% support |
| Pfam | PF00645 | zf-PARP — Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region | 176 / 312 | 56.4% | 62.9% of 280 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 248 / 312 | 79.5% | 90.8% of 273 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 248 / 312 | 79.5% | 90.8% of 273 | ≥50% support |
| GO | GO:0003909 Molecular Function | DNA ligase activity | 243 / 312 | 77.9% | 89.0% of 273 | ≥50% support |
| GO | GO:0071897 Biological Process | DNA biosynthetic process | 219 / 312 | 70.2% | 80.2% of 273 | ≥50% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 179 / 312 | 57.4% | 65.6% of 273 | ≥50% support |
| KEGG | K10776 | LIG3 — DNA repair and recombination proteins | 208 / 312 | 66.7% | 98.6% of 211 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000019640.1 | RMX38191.1 | hypothetical protein pdam_00003336 [Pocillopora damicornis] | – | JBrowse |
| Catostylus mosaicus | ENSSJYP00000019653.1 | RMX38191.1 | hypothetical protein pdam_00003336 [Pocillopora damicornis] | P97386 DNA ligase 3 OS=Mus musculus OX=10090 GN=Lig3 PE=1 SV=2 | JBrowse |
| Catostylus mosaicus | ENSSJYP00000019675.1 | XP_012555297.2 | DNA ligase 3 isoform X1 [Hydra vulgaris] | P49916 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 | JBrowse |
| Catostylus mosaicus | ENSSJYP00000019691.1 | XP_012555299.2 | DNA ligase 3 isoform X2 [Hydra vulgaris] | P49916 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 | JBrowse |