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This orthogroup contains 297 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 297 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11444 | ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE | 264 / 297 | 88.9% | 97.4% of 271 | ≥80% support |
| Pfam | PF00206 | Lyase_1 — Lyase | 261 / 297 | 87.9% | 97.4% of 268 | ≥80% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 270 / 297 | 90.9% | 99.6% of 271 | ≥80% support |
| GO | GO:0006099 Biological Process | tricarboxylic acid cycle | 265 / 297 | 89.2% | 97.8% of 271 | ≥80% support |
| GO | GO:0004333 Molecular Function | fumarate hydratase activity | 264 / 297 | 88.9% | 97.4% of 271 | ≥80% support |
| GO | GO:0006106 Biological Process | fumarate metabolic process | 264 / 297 | 88.9% | 97.4% of 271 | ≥80% support |
| GO | GO:0006108 Biological Process | malate metabolic process | 250 / 297 | 84.2% | 92.3% of 271 | ≥80% support |
| Pfam | PF10415 | FumaraseC_C — Fumarase C C-terminus | 225 / 297 | 75.8% | 84.0% of 268 | ≥50% support |
| GO | GO:0016829 Molecular Function | lyase activity | 225 / 297 | 75.8% | 83.0% of 271 | ≥50% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 220 / 297 | 74.1% | 81.2% of 271 | ≥50% support |
| KEGG | K01679 | E4.2.1.2B, fumC, FH — Cushing syndrome | 218 / 297 | 73.4% | 99.1% of 220 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000013892.1 | XP_002161201.2 | fumarate hydratase, mitochondrial [Hydra vulgaris] | P14408 Fumarate hydratase, mitochondrial OS=Rattus norvegicus OX=10 | JBrowse |
