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This orthogroup contains 296 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 296 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| GO | GO:0003723 Molecular Function | RNA binding | 246 / 296 | 83.1% | 98.0% of 251 | ≥80% support |
| PANTHER | PTHR18934 | ATP-DEPENDENT RNA HELICASE | 219 / 296 | 74.0% | 89.0% of 246 | ≥50% support |
| Pfam | PF04146 | YTH — YT521-B-like domain | 202 / 296 | 68.2% | 80.8% of 250 | ≥50% support |
| Pfam | PF21010 | HA2_C — Helicase associated domain (HA2), ratchet-like | 197 / 296 | 66.6% | 78.8% of 250 | ≥50% support |
| Pfam | PF00271 | Helicase_C — Helicase conserved C-terminal domain | 180 / 296 | 60.8% | 72.0% of 250 | ≥50% support |
| Pfam | PF04408 | HA2_N — Helicase associated domain (HA2), winged-helix | 177 / 296 | 59.8% | 70.8% of 250 | ≥50% support |
| Pfam | PF07717 | OB_NTP_bind — Oligonucleotide/oligosaccharide-binding (OB)-fold | 176 / 296 | 59.5% | 70.4% of 250 | ≥50% support |
| Pfam | PF00270 | DEAD | 161 / 296 | 54.4% | 64.4% of 250 | ≥50% support |
| Pfam | PF01424 | R3H | 159 / 296 | 53.7% | 63.6% of 250 | ≥50% support |
| GO | GO:0004386 Molecular Function | helicase activity | 219 / 296 | 74.0% | 87.3% of 251 | ≥50% support |
| GO | GO:0005622 Cellular Component | intracellular anatomical structure | 219 / 296 | 74.0% | 87.3% of 251 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 177 / 296 | 59.8% | 70.5% of 251 | ≥50% support |
| GO | GO:0003676 Molecular Function | nucleic acid binding | 173 / 296 | 58.5% | 68.9% of 251 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 161 / 296 | 54.4% | 64.1% of 251 | ≥50% support |
| KEGG | K20099 | YTHDC2 — Spliceosome | 155 / 296 | 52.4% | 95.1% of 163 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000010025.1 | XP_048584251.1 | 3'-5' RNA helicase YTHDC2 [Nematostella vectensis] | B2RR83 3'-5' RNA helicase YTHDC2 OS=Mus musculus OX=10090 GN=Ythdc2 | JBrowse |
| Catostylus mosaicus | ENSSJYP00000010035.1 | XP_047132909.1 | 3'-5' RNA helicase YTHDC2 isoform X2 [Hydra vulgaris] | Q9H6S0 3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 | JBrowse |
