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This orthogroup contains 279 genes from 133 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 279 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR36754 | E3 UBIQUITIN-PROTEIN LIGASE TRIM37 | 240 / 279 | 86.0% | 98.8% of 243 | ≥80% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 241 / 279 | 86.4% | 98.8% of 244 | ≥80% support |
| GO | GO:0005164 Molecular Function | tumor necrosis factor receptor binding | 240 / 279 | 86.0% | 98.4% of 244 | ≥80% support |
| GO | GO:0005777 Cellular Component | peroxisome | 240 / 279 | 86.0% | 98.4% of 244 | ≥80% support |
| GO | GO:0016235 Cellular Component | aggresome | 240 / 279 | 86.0% | 98.4% of 244 | ≥80% support |
| GO | GO:0031625 Molecular Function | ubiquitin protein ligase binding | 240 / 279 | 86.0% | 98.4% of 244 | ≥80% support |
| GO | GO:0032088 Biological Process | negative regulation of NF-kappaB transcription factor activity | 240 / 279 | 86.0% | 98.4% of 244 | ≥80% support |
| GO | GO:0046600 Biological Process | negative regulation of centriole replication | 240 / 279 | 86.0% | 98.4% of 244 | ≥80% support |
| GO | GO:0051092 Biological Process | positive regulation of NF-kappaB transcription factor activity | 240 / 279 | 86.0% | 98.4% of 244 | ≥80% support |
| GO | GO:0051865 Biological Process | protein autoubiquitination | 240 / 279 | 86.0% | 98.4% of 244 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 231 / 279 | 82.8% | 94.7% of 244 | ≥80% support |
| GO | GO:0016567 Biological Process | protein ubiquitination | 224 / 279 | 80.3% | 91.8% of 244 | ≥80% support |
| Pfam | PF00917 | MATH | 219 / 279 | 78.5% | 92.8% of 236 | ≥50% support |
| Pfam | PF00643 | zf-B_box — B-box zinc finger | 205 / 279 | 73.5% | 86.9% of 236 | ≥50% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 208 / 279 | 74.6% | 85.3% of 244 | ≥50% support |
| KEGG | K10608 | TRIM37, MUL — Ubiquitin system | 210 / 279 | 75.3% | 98.6% of 213 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000005472.1 | XP_020912901.1 | E3 ubiquitin-protein ligase TRIM37 isoform X2 [Exaiptasia diaphana] | Q6PCX9 E3 ubiquitin-protein ligase TRIM37 OS=Mus musculus OX=10090 | JBrowse |
