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This orthogroup contains 274 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 274 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11216 | EH DOMAIN | 212 / 274 | 77.4% | 93.8% of 226 | ≥50% support |
| Pfam | PF12763 | EF-hand_4 — Cytoskeletal-regulatory complex EF hand | 208 / 274 | 75.9% | 98.6% of 211 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 213 / 274 | 77.7% | 98.2% of 217 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 213 / 274 | 77.7% | 98.2% of 217 | ≥50% support |
| GO | GO:0006897 Biological Process | endocytosis | 212 / 274 | 77.4% | 97.7% of 217 | ≥50% support |
| GO | GO:0016197 Biological Process | endosomal transport | 212 / 274 | 77.4% | 97.7% of 217 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 209 / 274 | 76.3% | 96.3% of 217 | ≥50% support |
| GO | GO:0005509 Molecular Function | calcium ion binding | 195 / 274 | 71.2% | 89.9% of 217 | ≥50% support |
| GO | GO:0030132 Cellular Component | clathrin coat of coated pit | 170 / 274 | 62.0% | 78.3% of 217 | ≥50% support |
| GO | GO:0045296 Molecular Function | cadherin binding | 147 / 274 | 53.7% | 67.7% of 217 | ≥50% support |
| KEGG | K12472 | EPS15 — Membrane trafficking | 172 / 274 | 62.8% | 98.9% of 174 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000003160.1 | KAF6093590.1 | epidermal growth factor receptor pathway substrate 15 like 1 [Phyllostomus discolor] | Q9UBC2 Epidermal growth factor receptor substrate 15-like 1 OS=Homo | JBrowse |
| Catostylus mosaicus | ENSSJYP00000003168.1 | CAH3168123.1 | unnamed protein product, partial [Porites lobata] | Q9UBC2 Epidermal growth factor receptor substrate 15-like 1 OS=Homo | JBrowse |
