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This orthogroup contains 273 genes from 138 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 273 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12877 | RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR | 224 / 273 | 82.1% | 98.7% of 227 | ≥80% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 224 / 273 | 82.1% | 98.7% of 227 | ≥80% support |
| GO | GO:0030036 Biological Process | actin cytoskeleton organization | 224 / 273 | 82.1% | 98.7% of 227 | ≥80% support |
| GO | GO:0051496 Biological Process | positive regulation of stress fiber assembly | 223 / 273 | 81.7% | 98.2% of 227 | ≥80% support |
| Pfam | PF19056 | WD40_2 — WD40 repeated domain | 194 / 273 | 71.1% | 85.1% of 228 | ≥50% support |
| Pfam | PF19057 | PH_19 — PH domain | 183 / 273 | 67.0% | 80.3% of 228 | ≥50% support |
| Pfam | PF00621 | RhoGEF | 182 / 273 | 66.7% | 79.8% of 228 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 142 / 273 | 52.0% | 62.6% of 227 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000020355.1 | XP_047137837.1 | rho guanine nucleotide exchange factor 10 isoform X3 [Hydra vulgaris] | O15013 Rho guanine nucleotide exchange factor 10 OS=Homo sapiens OX | JBrowse |
| Catostylus mosaicus | ENSSJYP00000020364.1 | XP_047137836.1 | rho guanine nucleotide exchange factor 10 isoform X2 [Hydra vulgaris] | O15013 Rho guanine nucleotide exchange factor 10 OS=Homo sapiens OX | JBrowse |
