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This orthogroup contains 269 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 269 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13561 | DNA REPLICATION REGULATOR DPB11-RELATED | 236 / 269 | 87.7% | 100.0% of 236 | ≥80% support |
| Pfam | PF00533 | BRCT | 228 / 269 | 84.8% | 98.3% of 232 | ≥80% support |
| GO | GO:0006270 Biological Process | DNA replication initiation | 236 / 269 | 87.7% | 100.0% of 236 | ≥80% support |
| GO | GO:0007095 Biological Process | mitotic G2 DNA damage checkpoint signaling | 236 / 269 | 87.7% | 100.0% of 236 | ≥80% support |
| GO | GO:0033314 Biological Process | mitotic DNA replication checkpoint signaling | 236 / 269 | 87.7% | 100.0% of 236 | ≥80% support |
| Pfam | PF12738 | PTCB-BRCT — twin BRCT domain | 198 / 269 | 73.6% | 85.3% of 232 | ≥50% support |
| Pfam | PF21298 | TopBP1_BRCT0 — TopBP1, BRCT0 domain | 152 / 269 | 56.5% | 65.5% of 232 | ≥50% support |
| KEGG | K10728 | TOPBP1 — DNA repair and recombination proteins | 176 / 269 | 65.4% | 98.9% of 178 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000018103.1 | XP_031553463.1 | DNA topoisomerase 2-binding protein 1-like [Actinia tenebrosa] | Q800K6 DNA topoisomerase 2-binding protein 1-A OS=Xenopus laevis OX | JBrowse |
| Catostylus mosaicus | ENSSJYP00000018115.1 | XP_020897330.1 | DNA topoisomerase 2-binding protein 1 [Exaiptasia diaphana] | Q800K6 DNA topoisomerase 2-binding protein 1-A OS=Xenopus laevis OX | JBrowse |
