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This orthogroup contains 266 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 266 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11699 | ALDEHYDE DEHYDROGENASE-RELATED | 224 / 266 | 84.2% | 94.9% of 236 | ≥80% support |
| Pfam | PF00171 | Aldedh — Aldehyde dehydrogenase family | 228 / 266 | 85.7% | 95.4% of 239 | ≥80% support |
| GO | GO:0016491 Molecular Function | oxidoreductase activity | 231 / 266 | 86.8% | 96.3% of 240 | ≥80% support |
| GO | GO:0004029 Molecular Function | aldehyde dehydrogenase (NAD+) activity | 224 / 266 | 84.2% | 93.3% of 240 | ≥80% support |
| GO | GO:0016155 Molecular Function | formyltetrahydrofolate dehydrogenase activity | 224 / 266 | 84.2% | 93.3% of 240 | ≥80% support |
| GO | GO:0009058 Biological Process | biosynthetic process | 213 / 266 | 80.1% | 88.8% of 240 | ≥80% support |
| Pfam | PF00551 | Formyl_trans_N — Formyl transferase | 211 / 266 | 79.3% | 88.3% of 239 | ≥50% support |
| Pfam | PF00550 | PP-binding — Phosphopantetheine attachment site | 200 / 266 | 75.2% | 83.7% of 239 | ≥50% support |
| Pfam | PF02911 | Formyl_trans_C — Formyl transferase, C-terminal domain | 198 / 266 | 74.4% | 82.9% of 239 | ≥50% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 206 / 266 | 77.4% | 85.8% of 240 | ≥50% support |
| GO | GO:0016620 Molecular Function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | 190 / 266 | 71.4% | 79.2% of 240 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 163 / 266 | 61.3% | 67.9% of 240 | ≥50% support |
| GO | GO:0006730 Biological Process | one-carbon metabolic process | 163 / 266 | 61.3% | 67.9% of 240 | ≥50% support |
| GO | GO:0009258 Biological Process | 10-formyltetrahydrofolate catabolic process | 163 / 266 | 61.3% | 67.9% of 240 | ≥50% support |
| KEGG | K00289 | ALDH1L — One carbon pool by folate | 183 / 266 | 68.8% | 95.3% of 192 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000010971.1 | XP_029197029.2 | cytosolic 10-formyltetrahydrofolate dehydrogenase-like [Acropora millepora] | Q3SY69 Mitochondrial 10-formyltetrahydrofolate dehydrogenase OS=Hom | JBrowse |