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This orthogroup contains 258 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 258 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11516 | PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR | 235 / 258 | 91.1% | 99.2% of 237 | ≥80% support |
| Pfam | PF00676 | E1_dh — Dehydrogenase E1 component | 236 / 258 | 91.5% | 100.0% of 236 | ≥80% support |
| GO | GO:0004739 Molecular Function | pyruvate dehydrogenase (acetyl-transferring) activity | 236 / 258 | 91.5% | 99.6% of 237 | ≥80% support |
| GO | GO:0006086 Biological Process | acetyl-CoA biosynthetic process from pyruvate | 236 / 258 | 91.5% | 99.6% of 237 | ≥80% support |
| GO | GO:0016624 Molecular Function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | 236 / 258 | 91.5% | 99.6% of 237 | ≥80% support |
| GO | GO:0043231 Cellular Component | intracellular membrane-bounded organelle | 187 / 258 | 72.5% | 78.9% of 237 | ≥50% support |
| KEGG | K00161 | PDHA, pdhA — Diabetic cardiomyopathy | 201 / 258 | 77.9% | 90.5% of 222 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000016220.1 | XP_047128191.1 | pyruvate dehydrogenase E1 component subunit alpha, mitochondrial [Hydra vulgaris] | P29804 Pyruvate dehydrogenase E1 component subunit alpha, somatic f | JBrowse |
| Catostylus mosaicus | ENSSJYP00000016229.1 | XP_020911220.1 | pyruvate dehydrogenase E1 component subunit alpha, mitochondrial [Exaiptasia diaphana] | P29804 Pyruvate dehydrogenase E1 component subunit alpha, somatic f | JBrowse |
