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This orthogroup contains 245 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 245 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11630 | DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER | 212 / 245 | 86.5% | 99.5% of 213 | ≥80% support |
| Pfam | PF00493 | MCM | 205 / 245 | 83.7% | 96.2% of 213 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 213 / 245 | 86.9% | 100.0% of 213 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 213 / 245 | 86.9% | 100.0% of 213 | ≥80% support |
| GO | GO:0032508 Biological Process | DNA duplex unwinding | 213 / 245 | 86.9% | 100.0% of 213 | ≥80% support |
| GO | GO:0000724 Biological Process | double-strand break repair via homologous recombination | 212 / 245 | 86.5% | 99.5% of 213 | ≥80% support |
| GO | GO:0003697 Molecular Function | single-stranded DNA binding | 212 / 245 | 86.5% | 99.5% of 213 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 212 / 245 | 86.5% | 99.5% of 213 | ≥80% support |
| GO | GO:0017116 Molecular Function | single-stranded DNA helicase activity | 212 / 245 | 86.5% | 99.5% of 213 | ≥80% support |
| GO | GO:0042555 Cellular Component | MCM complex | 212 / 245 | 86.5% | 99.5% of 213 | ≥80% support |
| Pfam | PF17855 | MCM_lid — MCM AAA-lid domain | 190 / 245 | 77.6% | 89.2% of 213 | ≥50% support |
| Pfam | PF17207 | MCM_OB — MCM OB domain | 184 / 245 | 75.1% | 86.4% of 213 | ≥50% support |
| GO | GO:0016887 Molecular Function | ATP hydrolysis activity | 144 / 245 | 58.8% | 67.6% of 213 | ≥50% support |
| KEGG | K10738 | MCM9 — DNA replication proteins | 176 / 245 | 71.8% | 99.4% of 177 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000014472.1 | XP_029187907.2 | DNA helicase MCM9-like [Acropora millepora] | I0IUP4 DNA helicase MCM9 OS=Gallus gallus OX=9031 GN=MCM9 PE=1 SV=2 | JBrowse |
| Catostylus mosaicus | ENSSJYP00000014481.1 | XP_027055778.1 | DNA helicase MCM9-like [Pocillopora damicornis] | I0IUP4 DNA helicase MCM9 OS=Gallus gallus OX=9031 GN=MCM9 PE=1 SV=2 | JBrowse |