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This orthogroup contains 235 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 235 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24345 | SERINE/THREONINE-PROTEIN KINASE PLK | 183 / 235 | 77.9% | 98.4% of 186 | ≥50% support |
| Pfam | PF00069 | Pkinase — Protein kinase domain | 181 / 235 | 77.0% | 88.3% of 205 | ≥50% support |
| Pfam | PF18190 | Plk4_PB1 — Polo-like Kinase 4 Polo Box 1 | 179 / 235 | 76.2% | 87.3% of 205 | ≥50% support |
| Pfam | PF18409 | Plk4_PB2 — Polo-like Kinase 4 Polo Box 2 | 175 / 235 | 74.5% | 85.4% of 205 | ≥50% support |
| GO | GO:0004674 Molecular Function | protein serine/threonine kinase activity | 184 / 235 | 78.3% | 91.5% of 201 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 184 / 235 | 78.3% | 91.5% of 201 | ≥50% support |
| GO | GO:0007052 Biological Process | mitotic spindle organization | 184 / 235 | 78.3% | 91.5% of 201 | ≥50% support |
| GO | GO:0000776 Cellular Component | kinetochore | 183 / 235 | 77.9% | 91.0% of 201 | ≥50% support |
| GO | GO:0000922 Cellular Component | spindle pole | 183 / 235 | 77.9% | 91.0% of 201 | ≥50% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 183 / 235 | 77.9% | 91.0% of 201 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 183 / 235 | 77.9% | 91.0% of 201 | ≥50% support |
| GO | GO:0005813 Cellular Component | centrosome | 183 / 235 | 77.9% | 91.0% of 201 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 182 / 235 | 77.5% | 90.6% of 201 | ≥50% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 182 / 235 | 77.5% | 90.6% of 201 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 172 / 235 | 73.2% | 85.6% of 201 | ≥50% support |
| KEGG | K08863 | PLK4 — Chromosome and associated proteins | 160 / 235 | 68.1% | 99.4% of 161 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000022116.1 | XP_015766992.1 | PREDICTED: serine/threonine-protein kinase PLK4-like [Acropora digitifera] | A7SNN5 Serine/threonine-protein kinase PLK4 OS=Nematostella vectens | JBrowse |
| Catostylus mosaicus | ENSSJYP00000022128.1 | XP_002165681.3 | serine/threonine-protein kinase PLK4 isoform X1 [Hydra vulgaris] | A7SNN5 Serine/threonine-protein kinase PLK4 OS=Nematostella vectens | JBrowse |