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This orthogroup contains 183 genes from 137 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 183 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR16560 | ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN | 163 / 183 | 89.1% | 100.0% of 163 | ≥80% support |
| Pfam | PF06401 | Alpha-2-MRAP_C — Alpha-2-macroglobulin RAP, C-terminal domain | 162 / 183 | 88.5% | 98.8% of 164 | ≥80% support |
| Pfam | PF06400 | Alpha-2-MRAP_N — Alpha-2-macroglobulin RAP, N-terminal domain | 155 / 183 | 84.7% | 94.5% of 164 | ≥80% support |
| GO | GO:0050750 Molecular Function | low-density lipoprotein particle receptor binding | 164 / 183 | 89.6% | 100.0% of 164 | ≥80% support |
| GO | GO:0012505 Cellular Component | endomembrane system | 163 / 183 | 89.1% | 99.4% of 164 | ≥80% support |
| GO | GO:0048019 Molecular Function | receptor antagonist activity | 163 / 183 | 89.1% | 99.4% of 164 | ≥80% support |
| GO | GO:0048259 Biological Process | regulation of receptor-mediated endocytosis | 163 / 183 | 89.1% | 99.4% of 164 | ≥80% support |
| GO | GO:0005783 Cellular Component | endoplasmic reticulum | 162 / 183 | 88.5% | 98.8% of 164 | ≥80% support |
| GO | GO:0008201 Molecular Function | heparin binding | 162 / 183 | 88.5% | 98.8% of 164 | ≥80% support |
| KEGG | K22290 | LRPAP1 — Cholesterol metabolism | 149 / 183 | 81.4% | 99.3% of 150 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000018726.1 | XP_027044862.1 | alpha-2-macroglobulin receptor-associated protein-like [Pocillopora damicornis] | P30533 Alpha-2-macroglobulin receptor-associated protein OS=Homo sa | JBrowse |
