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Support counts the member genes carrying the term. % of genes is that count over all 474 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR48099 | C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED | 306 / 474 | 64.6% | 96.2% of 318 | ≥50% support |
| Pfam | PF02882 | THF_DHG_CYH_C — Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain | 297 / 474 | 62.7% | 71.4% of 416 | ≥50% support |
| Pfam | PF00763 | THF_DHG_CYH — Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain | 277 / 474 | 58.4% | 66.6% of 416 | ≥50% support |
| Pfam | PF01268 | FTHFS — Formate--tetrahydrofolate ligase | 243 / 474 | 51.3% | 58.4% of 416 | ≥50% support |
| GO | GO:0004488 Molecular Function | methylenetetrahydrofolate dehydrogenase (NADP+) activity | 309 / 474 | 65.2% | 74.6% of 414 | ≥50% support |
| GO | GO:0005829 Cellular Component | cytosol | 308 / 474 | 65.0% | 74.4% of 414 | ≥50% support |
| GO | GO:0004477 Molecular Function | methenyltetrahydrofolate cyclohydrolase activity | 306 / 474 | 64.6% | 73.9% of 414 | ≥50% support |
| GO | GO:0035999 Biological Process | tetrahydrofolate interconversion | 306 / 474 | 64.6% | 73.9% of 414 | ≥50% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 255 / 474 | 53.8% | 61.6% of 414 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 244 / 474 | 51.5% | 58.9% of 414 | ≥50% support |
| GO | GO:0004329 Molecular Function | formate-tetrahydrofolate ligase activity | 243 / 474 | 51.3% | 58.7% of 414 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Cassiopea xamachana | Cxam_g18351.t1 | MBI3786069.1 | formate--tetrahydrofolate ligase [Deltaproteobacteria bacterium] | Q3A9K2 Formate--tetrahydrofolate ligase OS=Carboxydothermus hydroge | JBrowse |
| Cassiopea xamachana | Cxam_g2262.t1 | WP_171238135.1 | MULTISPECIES: formate--tetrahydrofolate ligase [unclassified Ruegeria] | Q1GE26 Formate--tetrahydrofolate ligase OS=Ruegeria sp. (strain TM1 | JBrowse |
| Cassiopea xamachana | Cxam_g2264.t1 | WP_155143328.1 | MULTISPECIES: bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD [Alphaproteobacteria] | Q5LNV2 Bifunctional protein FolD 1/3 OS=Ruegeria pomeroyi (strain A | JBrowse |
| Cassiopea xamachana | Cxam_g23516.t1 | XP_047139218.1 | C-1-tetrahydrofolate synthase, cytoplasmic isoform X1 [Hydra vulgaris] | P27653 C-1-tetrahydrofolate synthase, cytoplasmic OS=Rattus norvegi | JBrowse |
| Cassiopea xamachana | Cxam_g238.t1 | WP_170466608.1 | adenosine kinase [Ruegeria sp. SCSIO 43209] | Q55480 Uncharacterized sugar kinase slr0537 OS=Synechocystis sp. (s | JBrowse |
| Cassiopea xamachana | Cxam_g28952.t1 | XP_047137976.1 | C-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Hydra vulgaris] | Q922D8 C-1-tetrahydrofolate synthase, cytoplasmic OS=Mus musculus O | JBrowse |
| Cassiopea xamachana | Cxam_g6346.t1 | MBN2490587.1 | bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase [Planctomycetota bacterium] | A9ISZ5 Bifunctional protein FolD OS=Bordetella petrii (strain ATCC | JBrowse |
