← Back to the gene family browser
This orthogroup contains 142 genes from 109 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 142 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR14903 | SCLEROSTIN-RELATED | 126 / 142 | 88.7% | 100.0% of 126 | ≥80% support |
| Pfam | PF05463 | Sclerostin | 126 / 142 | 88.7% | 98.4% of 128 | ≥80% support |
| GO | GO:0005615 Cellular Component | extracellular space | 126 / 142 | 88.7% | 100.0% of 126 | ≥80% support |
| GO | GO:0030178 Biological Process | negative regulation of Wnt signaling pathway | 126 / 142 | 88.7% | 100.0% of 126 | ≥80% support |
| GO | GO:0030514 Biological Process | negative regulation of BMP signaling pathway | 126 / 142 | 88.7% | 100.0% of 126 | ≥80% support |
| GO | GO:0036122 Molecular Function | BMP binding | 126 / 142 | 88.7% | 100.0% of 126 | ≥80% support |
| KEGG | K25738 | SOSTDC1 — Signaling proteins | 87 / 142 | 61.3% | 93.6% of 93 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Desmophyllum pertusum | KAJ7381242.1 | KAJ7381242.1 | Sclerostin domain-containing protein 1 [Desmophyllum pertusum] | – | JBrowse |
