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This orthogroup contains 142 genes from 109 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 142 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR14903 | SCLEROSTIN-RELATED | 126 / 142 | 88.7% | 100.0% of 126 | ≥80% support |
| Pfam | PF05463 | Sclerostin | 126 / 142 | 88.7% | 98.4% of 128 | ≥80% support |
| GO | GO:0005615 Cellular Component | extracellular space | 126 / 142 | 88.7% | 100.0% of 126 | ≥80% support |
| GO | GO:0030178 Biological Process | negative regulation of Wnt signaling pathway | 126 / 142 | 88.7% | 100.0% of 126 | ≥80% support |
| GO | GO:0030514 Biological Process | negative regulation of BMP signaling pathway | 126 / 142 | 88.7% | 100.0% of 126 | ≥80% support |
| GO | GO:0036122 Molecular Function | BMP binding | 126 / 142 | 88.7% | 100.0% of 126 | ≥80% support |
| KEGG | K25738 | SOSTDC1 — Signaling proteins | 87 / 142 | 61.3% | 93.6% of 93 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora acuminata | aacu_s0342.g4.t1 | XP_015757009.1 | PREDICTED: sclerostin domain-containing protein 1-like [Acropora digitifera] | – | JBrowse |
| Alatina alata | Aala_g1562.t1 | KAJ4939272.1 | hypothetical protein JOQ06_028728, partial [Pogonophryne albipinna] | O02751 Craniofacial development protein 2 OS=Bos taurus OX=9913 GN= | JBrowse |
| Alatina alata | Aala_g516.t1 | XP_015284769.1 | PREDICTED: cytochrome P450 3A19-like, partial [Gekko japonicus] | Q29496 Cytochrome P450 3A24 OS=Ovis aries OX=9940 GN=CYP3A24 PE=2 S | JBrowse |
| Aurelia aurita | scaffold7.g69.t1 | none | – | JBrowse | |
| Aurelia aurita complex sp. Pacific | scaffold109.g21.t1 | none | – | JBrowse | |
| Acropora austera | ENSKKQP00000042300.1 | XP_015757009.1 | PREDICTED: sclerostin domain-containing protein 1-like [Acropora digitifera] | – | JBrowse |
| Acropora awi | aawi_s0187.g9.t1 | XP_015757009.1 | PREDICTED: sclerostin domain-containing protein 1-like [Acropora digitifera] | – | JBrowse |
| Acropora cervicornis | KAK2570075.1 | XP_015757009.1 | PREDICTED: sclerostin domain-containing protein 1-like [Acropora digitifera] | – | JBrowse |
| Acropora cytherea | acyt_s0050.g157.t1 | XP_015757009.1 | PREDICTED: sclerostin domain-containing protein 1-like [Acropora digitifera] | – | JBrowse |
| Acropora digitifera | chr8Alt.g17402.t1 | none | – | JBrowse | |
| Acropora echinata | aech_s0170.g9.t1 | XP_015757009.1 | PREDICTED: sclerostin domain-containing protein 1-like [Acropora digitifera] | – | JBrowse |
| Actinia equina | EGACTEQ4350036057-PA | XP_031560554.1 | sclerostin domain-containing protein 1-like [Actinia tenebrosa] | – | JBrowse |
| Acropora florida | aflo_s0085.g8.t1 | XP_015757009.1 | PREDICTED: sclerostin domain-containing protein 1-like [Acropora digitifera] | – | JBrowse |
| Acropora gemmifera | agem_s0117.g18.t1 | XP_015757009.1 | PREDICTED: sclerostin domain-containing protein 1-like [Acropora digitifera] | – | JBrowse |
| Acropora hemprichii | Ahemp_010948-T1 | XP_015757009.1 | PREDICTED: sclerostin domain-containing protein 1-like [Acropora digitifera] | – | JBrowse |
| Acropora hyacinthus | ahya_s0045.g9.t1 | XP_015757009.1 | PREDICTED: sclerostin domain-containing protein 1-like [Acropora digitifera] | – | JBrowse |
| Alvinactis idsseensis sp. Nov. | alvinactis_v1_g402 | XP_031560554.1 | sclerostin domain-containing protein 1-like [Actinia tenebrosa] | – | JBrowse |
| Acropora intermedia | aint_s0092.g6.t1 | XP_015757009.1 | PREDICTED: sclerostin domain-containing protein 1-like [Acropora digitifera] | – | JBrowse |
| Actinoscyphia liui | gene11110.t1 | XP_020917250.1 | sclerostin domain-containing protein 1 [Exaiptasia diaphana] | – | JBrowse |
| Acropora loripes | alor_g17947.t1 | XP_015757009.1 | PREDICTED: sclerostin domain-containing protein 1-like [Acropora digitifera] | – | JBrowse |
