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This orthogroup contains 260 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 260 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13428 | INNER NUCLEAR MEMBRANE PROTEIN MAN1 LEM DOMAIN CONTAINING PROTEIN | 217 / 260 | 83.5% | 99.1% of 219 | ≥80% support |
| GO | GO:0006998 Biological Process | nuclear envelope organization | 217 / 260 | 83.5% | 100.0% of 217 | ≥80% support |
| GO | GO:0031490 Molecular Function | chromatin DNA binding | 217 / 260 | 83.5% | 100.0% of 217 | ≥80% support |
| GO | GO:0030514 Biological Process | negative regulation of BMP signaling pathway | 215 / 260 | 82.7% | 99.1% of 217 | ≥80% support |
| Pfam | PF09402 | MSC — Man1-Src1p-C-terminal domain | 174 / 260 | 66.9% | 84.5% of 206 | ≥50% support |
| Pfam | PF03020 | LEM | 168 / 260 | 64.6% | 81.6% of 206 | ≥50% support |
| GO | GO:0003676 Molecular Function | nucleic acid binding | 173 / 260 | 66.5% | 79.7% of 217 | ≥50% support |
| KEGG | K19410 | LEMD3 — Cytoskeleton proteins | 152 / 260 | 58.5% | 99.4% of 153 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Edwardsia elegans | jg28714.t1 | EDO41725.1 | predicted protein [Nematostella vectensis] | Q9Y2U8 Inner nuclear membrane protein Man1 OS=Homo sapiens OX=9606 | JBrowse |
| Edwardsia elegans | jg28715.t1 | XP_048589659.1 | inner nuclear membrane protein Man1 isoform X1 [Nematostella vectensis] | Q9Y2U8 Inner nuclear membrane protein Man1 OS=Homo sapiens OX=9606 | JBrowse |
| Edwardsia elegans | jg28715.t2 | XP_048589660.1 | inner nuclear membrane protein Man1 isoform X2 [Nematostella vectensis] | Q9Y2U8 Inner nuclear membrane protein Man1 OS=Homo sapiens OX=9606 | JBrowse |
