Gene Family

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Member genes
559
Species
143
Sequences
559
Best annotation support
87.5%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 87.5% of the 559 members.

Support counts the member genes carrying the term. % of genes is that count over all 559 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR45627ADENYLATE CYCLASE TYPE 1489 / 55987.5%100.0%
of 489
≥80% support
PfamPF00211Guanylate_cyc — Adenylate and Guanylate cyclase catalytic domain456 / 55981.6%94.4%
of 483
≥80% support
GOGO:0004016
Molecular Function
adenylate cyclase activity489 / 55987.5%100.0%
of 489
≥80% support
GOGO:0005887
Cellular Component
plasma membrane489 / 55987.5%100.0%
of 489
≥80% support
GOGO:0007189
Biological Process
adenylate cyclase-activating G protein-coupled receptor signaling pathway489 / 55987.5%100.0%
of 489
≥80% support
GOGO:0009190
Biological Process
cyclic nucleotide biosynthetic process456 / 55981.6%93.3%
of 489
≥80% support
GOGO:0035556
Biological Process
intracellular signal transduction456 / 55981.6%93.3%
of 489
≥80% support
PfamPF16214AC_N — Adenylyl cyclase N-terminal extracellular and transmembrane region366 / 55965.5%75.8%
of 483
≥50% support
GOGO:0016849
Molecular Function
phosphorus-oxygen lyase activity364 / 55965.1%74.4%
of 489
≥50% support
GOGO:0006171
Biological Process
cAMP biosynthetic process297 / 55953.1%60.7%
of 489
≥50% support
GOGO:0005886
Cellular Component
plasma membrane296 / 55953.0%60.5%
of 489
≥50% support
📊 Total members in OG0001378: 11 (filtered to HECHI · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Hydractinia echinataENSDJXP00000033894.1XP_047136993.1adenylate cyclase type 5 isoform X1 [Hydra vulgaris]P84309
Adenylate cyclase type 5 OS=Mus musculus OX=10090 GN=Adcy5 P
JBrowse
Hydractinia echinataENSDJXP00000033910.1XP_047136993.1adenylate cyclase type 5 isoform X1 [Hydra vulgaris]P84309
Adenylate cyclase type 5 OS=Mus musculus OX=10090 GN=Adcy5 P
JBrowse
Hydractinia echinataENSDJXP00000037365.1XP_047144841.1adenylate cyclase type 2 isoform X2 [Hydra vulgaris]Q8VHH7
Adenylate cyclase type 3 OS=Mus musculus OX=10090 GN=Adcy3 P
JBrowse
Hydractinia echinataENSDJXP00000037375.1XP_047144841.1adenylate cyclase type 2 isoform X2 [Hydra vulgaris]Q8VHH7
Adenylate cyclase type 3 OS=Mus musculus OX=10090 GN=Adcy3 P
JBrowse
Hydractinia echinataENSDJXP00000037404.1XP_047144841.1adenylate cyclase type 2 isoform X2 [Hydra vulgaris]Q8VHH7
Adenylate cyclase type 3 OS=Mus musculus OX=10090 GN=Adcy3 P
JBrowse
Hydractinia echinataENSDJXP00000049435.1XP_047144840.1adenylate cyclase type 7 isoform X1 [Hydra vulgaris]P30804
Adenylate cyclase type 6 OS=Canis lupus familiaris OX=9615 G
JBrowse
Hydractinia echinataENSDJXP00000049439.1XP_047144840.1adenylate cyclase type 7 isoform X1 [Hydra vulgaris]P30804
Adenylate cyclase type 6 OS=Canis lupus familiaris OX=9615 G
JBrowse
Hydractinia echinataENSDJXP00000049447.1XP_047144840.1adenylate cyclase type 7 isoform X1 [Hydra vulgaris]O43306
Adenylate cyclase type 6 OS=Homo sapiens OX=9606 GN=ADCY6 PE
JBrowse
Hydractinia echinataENSDJXP00000049461.1XP_047144841.1adenylate cyclase type 2 isoform X2 [Hydra vulgaris]O43306
Adenylate cyclase type 6 OS=Homo sapiens OX=9606 GN=ADCY6 PE
JBrowse
Hydractinia echinataENSDJXP00000049472.1XP_047144841.1adenylate cyclase type 2 isoform X2 [Hydra vulgaris]O43306
Adenylate cyclase type 6 OS=Homo sapiens OX=9606 GN=ADCY6 PE
JBrowse
Hydractinia echinataENSDJXP00000055525.1XP_047144841.1adenylate cyclase type 2 isoform X2 [Hydra vulgaris]Q04400
Adenylate cyclase type 5 OS=Rattus norvegicus OX=10116 GN=Ad
JBrowse
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