Gene Family

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Member genes
202
Species
137
Sequences
202
Best annotation support
84.2%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 84.2% of the 202 members.

Support counts the member genes carrying the term. % of genes is that count over all 202 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PfamPF14048MBD_C — C-terminal domain of methyl-CpG binding protein 2 and 3170 / 20284.2%93.9%
of 181
≥80% support
GOGO:0003677
Molecular Function
DNA binding175 / 20286.6%99.4%
of 176
≥80% support
PANTHERPTHR12396METHYL-CPG BINDING PROTEIN, MBD157 / 20277.7%99.4%
of 158
≥50% support
PfamPF01429MBD — Methyl-CpG binding domain161 / 20279.7%89.0%
of 181
≥50% support
GOGO:0000122
Biological Process
negative regulation of transcription by RNA polymerase II151 / 20274.8%85.8%
of 176
≥50% support
GOGO:0005634
Cellular Component
nucleus151 / 20274.8%85.8%
of 176
≥50% support
GOGO:0006346
Biological Process
DNA methylation-dependent constitutive heterochromatin formation151 / 20274.8%85.8%
of 176
≥50% support
GOGO:0008327
Molecular Function
methyl-CpG binding151 / 20274.8%85.8%
of 176
≥50% support
KEGGK11590MBD2 — Chromosome and associated proteins157 / 20277.7%98.7%
of 159
≥50% support
📊 Total members in OG0007280: 4 (filtered to HOCTO · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Haliclystus octoradiatus18431_t.1noneJBrowse
Haliclystus octoradiatusBRAKERHOCP00005000260.1XP_047140768.1methyl-CpG-binding domain protein 2 [Hydra vulgaris]Q9UBB5
Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606
JBrowse
Haliclystus octoradiatusBRAKERHOCP00005002369.1XP_047140768.1methyl-CpG-binding domain protein 2 [Hydra vulgaris]Q9UBB5
Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606
JBrowse
Haliclystus octoradiatusg5256.t1.1noneJBrowse
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