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🧬 OG0004180

This orthogroup contains 265 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 75.1%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 265 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR11630DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER199 / 26575.1%99.5%
of 200		≥50% support
PfamPF00493MCM187 / 26570.6%88.6%
of 211		≥50% support
PfamPF18263MCM6_C — MCM6 C-terminal winged-helix domain179 / 26567.6%84.8%
of 211		≥50% support
PfamPF17207MCM_OB — MCM OB domain179 / 26567.6%84.8%
of 211		≥50% support
PfamPF17855MCM_lid — MCM AAA-lid domain178 / 26567.2%84.4%
of 211		≥50% support
PfamPF14551MCM_N — MCM N-terminal domain169 / 26563.8%80.1%
of 211		≥50% support
GOGO:0003677
Molecular Function		DNA binding200 / 26575.5%100.0%
of 200		≥50% support
GOGO:0042555
Cellular Component		MCM complex200 / 26575.5%100.0%
of 200		≥50% support
GOGO:0005634
Cellular Component		nucleus200 / 26575.5%100.0%
of 200		≥50% support
GOGO:0005524
Molecular Function		ATP binding200 / 26575.5%100.0%
of 200		≥50% support
GOGO:0017116
Molecular Function		single-stranded DNA helicase activity199 / 26575.1%99.5%
of 200		≥50% support
GOGO:0032508
Biological Process		DNA duplex unwinding199 / 26575.1%99.5%
of 200		≥50% support
GOGO:0006268
Biological Process		DNA unwinding involved in DNA replication199 / 26575.1%99.5%
of 200		≥50% support
GOGO:1902969
Biological Process		mitotic DNA replication199 / 26575.1%99.5%
of 200		≥50% support
GOGO:1990518
Molecular Function		single-stranded 3'-5' DNA helicase activity199 / 26575.1%99.5%
of 200		≥50% support
GOGO:0003697
Molecular Function		single-stranded DNA binding199 / 26575.1%99.5%
of 200		≥50% support
GOGO:0000727
Biological Process		double-strand break repair via break-induced replication199 / 26575.1%99.5%
of 200		≥50% support
GOGO:0006270
Biological Process		DNA replication initiation178 / 26567.2%89.0%
of 200		≥50% support
GOGO:0003678
Molecular Function		DNA helicase activity178 / 26567.2%89.0%
of 200		≥50% support
GOGO:0006260
Biological Process		DNA replication169 / 26563.8%84.5%
of 200		≥50% support
KEGGK02542MCM6 — DNA replication proteins167 / 26563.0%99.4%
of 168		≥50% support
📊 Total members in OG0004180: 3 (filtered to LPERT · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)		 Top NCBI-NR hit description
(source organism)		 Top UniProt hit
(Swiss-Prot)		 Genome browser
Lophelia pertusaOS493_036872-T1KAJ7376108.1MCM DNA helicase complex subunit mcm6 [Desmophyllum pertusum]Q498J7
Zygotic DNA replication licensing factor mcm6-A OS=Xenopus l		JBrowse
Lophelia pertusaOS493_036877-T1KAJ7376113.1MCM DNA helicase complex subunit mcm6 [Desmophyllum pertusum]Q14566
DNA replication licensing factor MCM6 OS=Homo sapiens OX=960		JBrowse
Lophelia pertusaOS493_036878-T1KAJ7376114.1MCM DNA helicase complex subunit mcm6, partial [Desmophyllum pertusum]P97311
DNA replication licensing factor MCM6 OS=Mus musculus OX=100		JBrowse
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