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This orthogroup contains 241 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 241 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45625 | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED | 204 / 241 | 84.7% | 97.1% of 210 | ≥80% support |
| Pfam | PF00160 | Pro_isomerase — Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD | 205 / 241 | 85.1% | 97.2% of 211 | ≥80% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 207 / 241 | 85.9% | 95.8% of 216 | ≥80% support |
| GO | GO:0000413 Biological Process | protein peptidyl-prolyl isomerization | 205 / 241 | 85.1% | 94.9% of 216 | ≥80% support |
| GO | GO:0003755 Molecular Function | peptidyl-prolyl cis-trans isomerase activity | 205 / 241 | 85.1% | 94.9% of 216 | ≥80% support |
| GO | GO:0000209 Biological Process | protein polyubiquitination | 204 / 241 | 84.7% | 94.4% of 216 | ≥80% support |
| GO | GO:0071013 Cellular Component | catalytic step 2 spliceosome | 204 / 241 | 84.7% | 94.4% of 216 | ≥80% support |
| GO | GO:0004842 Molecular Function | ubiquitin-protein transferase activity | 193 / 241 | 80.1% | 89.4% of 216 | ≥80% support |
| GO | GO:0016567 Biological Process | protein ubiquitination | 193 / 241 | 80.1% | 89.4% of 216 | ≥80% support |
| Pfam | PF04641 | Rtf2 | 180 / 241 | 74.7% | 85.3% of 211 | ≥50% support |
| GO | GO:0006457 Biological Process | protein folding | 168 / 241 | 69.7% | 77.8% of 216 | ≥50% support |
| KEGG | K10598 | PPIL2, CYC4, CHP60 — Ubiquitin system | 185 / 241 | 76.8% | 98.4% of 188 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Lophelia pertusa | OS493_036941-T1 | KAJ7382103.1 | RING-type E3 ubiquitin-protein ligase ppil2, partial [Desmophyllum pertusum] | Q13356 RING-type E3 ubiquitin-protein ligase PPIL2 OS=Homo sapiens | JBrowse |
| Lophelia pertusa | OS493_036955-T1 | KAJ7382116.1 | RING-type E3 ubiquitin-protein ligase ppil2 [Desmophyllum pertusum] | Q9D787 RING-type E3 ubiquitin-protein ligase PPIL2 OS=Mus musculus | JBrowse |
