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This orthogroup contains 928 genes from 147 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 928 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10336 | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN | 786 / 928 | 84.7% | 99.4% of 791 | ≥80% support |
| GO | GO:0035556 Biological Process | intracellular signal transduction | 789 / 928 | 85.0% | 99.5% of 793 | ≥80% support |
| GO | GO:0004435 Molecular Function | phosphatidylinositol phospholipase C activity | 787 / 928 | 84.8% | 99.2% of 793 | ≥80% support |
| GO | GO:0048015 Biological Process | phosphatidylinositol-mediated signaling | 785 / 928 | 84.6% | 99.0% of 793 | ≥80% support |
| GO | GO:0051209 Biological Process | release of sequestered calcium ion into cytosol | 785 / 928 | 84.6% | 99.0% of 793 | ≥80% support |
| GO | GO:0006629 Biological Process | lipid metabolic process | 749 / 928 | 80.7% | 94.5% of 793 | ≥80% support |
| GO | GO:0008081 Molecular Function | phosphoric diester hydrolase activity | 749 / 928 | 80.7% | 94.5% of 793 | ≥80% support |
| Pfam | PF00388 | PI-PLC-X — Phosphatidylinositol-specific phospholipase C, X domain | 654 / 928 | 70.5% | 82.3% of 795 | ≥50% support |
| Pfam | PF00387 | PI-PLC-Y — Phosphatidylinositol-specific phospholipase C, Y domain | 647 / 928 | 69.7% | 81.4% of 795 | ≥50% support |
| Pfam | PF00168 | C2 | 635 / 928 | 68.4% | 79.9% of 795 | ≥50% support |
| Pfam | PF09279 | EF-hand_like — Phosphoinositide-specific phospholipase C, efhand-like | 585 / 928 | 63.0% | 73.6% of 795 | ≥50% support |
| GO | GO:0007165 Biological Process | signal transduction | 656 / 928 | 70.7% | 82.7% of 793 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000002817.1 | XP_028399821.1 | inactive phospholipase C-like protein 2 [Dendronephthya gigantea] | Q9UPR0 Inactive phospholipase C-like protein 2 OS=Homo sapiens OX=9 | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000002824.1 | XP_028399821.1 | inactive phospholipase C-like protein 2 [Dendronephthya gigantea] | Q9UPR0 Inactive phospholipase C-like protein 2 OS=Homo sapiens OX=9 | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000005212.1 | CAB4021647.1 | inactive phospholipase C 2 [Paramuricea clavata] | Q9UPR0 Inactive phospholipase C-like protein 2 OS=Homo sapiens OX=9 | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000024835.1 | XP_028404786.1 | LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2-like [Dendronephthya gigantea] | Q8SPR7 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase de | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000024857.1 | XP_028404786.1 | LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2-like [Dendronephthya gigantea] | Q32NH8 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase de | JBrowse |