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This orthogroup contains 642 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 642 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10259 | THIOPURINE S-METHYLTRANSFERASE | 561 / 642 | 87.4% | 100.0% of 561 | ≥80% support |
| Pfam | PF05724 | TPMT | 562 / 642 | 87.5% | 100.0% of 562 | ≥80% support |
| GO | GO:0008757 Molecular Function | S-adenosylmethionine-dependent methyltransferase activity | 562 / 642 | 87.5% | 99.5% of 565 | ≥80% support |
| GO | GO:0008119 Molecular Function | thiopurine S-methyltransferase activity | 561 / 642 | 87.4% | 99.3% of 565 | ≥80% support |
| KEGG | K00569 | TPMT, tpmT — Drug metabolism - other enzymes | 358 / 642 | 55.8% | 99.2% of 361 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000022271.1 | CAB4033218.1 | thiopurine S-methyltransferase-like, partial [Paramuricea clavata] | A9I3K3 Thiopurine S-methyltransferase OS=Bordetella petrii (strain | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000022279.1 | XP_028397722.1 | probable thiopurine S-methyltransferase [Dendronephthya gigantea] | A6V3Q8 Thiopurine S-methyltransferase OS=Pseudomonas paraeruginosa | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000024023.1 | XP_028397722.1 | probable thiopurine S-methyltransferase [Dendronephthya gigantea] | Q1Q8I2 Thiopurine S-methyltransferase OS=Psychrobacter cryohalolent | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000024032.1 | XP_028397722.1 | probable thiopurine S-methyltransferase [Dendronephthya gigantea] | Q1Q8I2 Thiopurine S-methyltransferase OS=Psychrobacter cryohalolent | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000024038.1 | XP_028397722.1 | probable thiopurine S-methyltransferase [Dendronephthya gigantea] | Q3BCR4 Thiopurine S-methyltransferase OS=Chlorocebus aethiops OX=95 | JBrowse |
