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This orthogroup contains 545 genes from 149 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 545 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23281 | MERLIN/MOESIN/EZRIN/RADIXIN | 487 / 545 | 89.4% | 99.8% of 488 | ≥80% support |
| Pfam | PF00373 | FERM_M — FERM central domain | 437 / 545 | 80.2% | 89.9% of 486 | ≥80% support |
| GO | GO:0003779 Molecular Function | actin binding | 489 / 545 | 89.7% | 99.8% of 490 | ≥80% support |
| GO | GO:0008360 Biological Process | regulation of cell shape | 487 / 545 | 89.4% | 99.4% of 490 | ≥80% support |
| GO | GO:0030175 Cellular Component | filopodium | 487 / 545 | 89.4% | 99.4% of 490 | ≥80% support |
| GO | GO:0050839 Molecular Function | cell adhesion molecule binding | 487 / 545 | 89.4% | 99.4% of 490 | ≥80% support |
| GO | GO:1902115 Biological Process | regulation of organelle assembly | 487 / 545 | 89.4% | 99.4% of 490 | ≥80% support |
| GO | GO:1902966 Biological Process | positive regulation of protein localization to early endosome | 487 / 545 | 89.4% | 99.4% of 490 | ≥80% support |
| GO | GO:2000643 Biological Process | positive regulation of early endosome to late endosome transport | 487 / 545 | 89.4% | 99.4% of 490 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 472 / 545 | 86.6% | 96.3% of 490 | ≥80% support |
| GO | GO:0005912 Cellular Component | adherens junction | 472 / 545 | 86.6% | 96.3% of 490 | ≥80% support |
| GO | GO:0045177 Cellular Component | apical part of cell | 472 / 545 | 86.6% | 96.3% of 490 | ≥80% support |
| GO | GO:0008092 Molecular Function | cytoskeletal protein binding | 463 / 545 | 85.0% | 94.5% of 490 | ≥80% support |
| GO | GO:0005856 Cellular Component | cytoskeleton | 459 / 545 | 84.2% | 93.7% of 490 | ≥80% support |
| Pfam | PF09380 | FERM_C — FERM C-terminal PH-like domain | 435 / 545 | 79.8% | 89.5% of 486 | ≥50% support |
| Pfam | PF09379 | FERM_N — FERM N-terminal domain | 414 / 545 | 76.0% | 85.2% of 486 | ≥50% support |
| Pfam | PF00769 | ERM_C — Ezrin/radixin/moesin family C terminal | 401 / 545 | 73.6% | 82.5% of 486 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000032894.1 | XP_028412096.1 | moesin-like [Dendronephthya gigantea] | Q66I42 Moesin a OS=Danio rerio OX=7955 GN=msna PE=1 SV=1 | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000032906.1 | XP_028412096.1 | moesin-like [Dendronephthya gigantea] | Q66I42 Moesin a OS=Danio rerio OX=7955 GN=msna PE=1 SV=1 | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000035495.1 | CAB4000471.1 | radixin [Paramuricea clavata] | P35241 Radixin OS=Homo sapiens OX=9606 GN=RDX PE=1 SV=1 | JBrowse |
