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This orthogroup contains 501 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 501 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR46026 | RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F | 377 / 501 | 75.3% | 97.9% of 385 | ≥50% support |
| Pfam | PF00621 | RhoGEF | 346 / 501 | 69.1% | 85.4% of 405 | ≥50% support |
| Pfam | PF16614 | RhoGEF67_u2 — Unstructured region two on RhoGEF 6 and 7 | 315 / 501 | 62.9% | 77.8% of 405 | ≥50% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 377 / 501 | 75.3% | 97.4% of 387 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 377 / 501 | 75.3% | 97.4% of 387 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 346 / 501 | 69.1% | 89.4% of 387 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000025174.1 | CAB3984341.1 | Rho guanine nucleotide exchange factor 7, partial [Paramuricea clavata] | Q14155 Rho guanine nucleotide exchange factor 7 OS=Homo sapiens OX= | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000025188.1 | CAB3984340.1 | Rho guanine nucleotide exchange factor 7 [Paramuricea clavata] | Q14155 Rho guanine nucleotide exchange factor 7 OS=Homo sapiens OX= | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000025204.1 | XP_028401638.1 | rho guanine nucleotide exchange factor 7-like isoform X1 [Dendronephthya gigantea] | Q14155 Rho guanine nucleotide exchange factor 7 OS=Homo sapiens OX= | JBrowse |
