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This orthogroup contains 485 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 485 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45689 | I[[H]] CHANNEL, ISOFORM E | 424 / 485 | 87.4% | 99.8% of 425 | ≥80% support |
| GO | GO:0003254 Biological Process | regulation of membrane depolarization | 424 / 485 | 87.4% | 99.8% of 425 | ≥80% support |
| GO | GO:0005249 Molecular Function | voltage-gated potassium channel activity | 424 / 485 | 87.4% | 99.8% of 425 | ≥80% support |
| GO | GO:0035725 Biological Process | sodium ion transmembrane transport | 424 / 485 | 87.4% | 99.8% of 425 | ≥80% support |
| GO | GO:0071805 Biological Process | potassium ion transmembrane transport | 424 / 485 | 87.4% | 99.8% of 425 | ≥80% support |
| GO | GO:0098855 Cellular Component | HCN channel complex | 424 / 485 | 87.4% | 99.8% of 425 | ≥80% support |
| Pfam | PF00027 | cNMP_binding — Cyclic nucleotide-binding domain | 369 / 485 | 76.1% | 86.6% of 426 | ≥50% support |
| Pfam | PF00520 | Ion_trans — Ion transport protein | 358 / 485 | 73.8% | 84.0% of 426 | ≥50% support |
| Pfam | PF08412 | Ion_trans_N — Ion transport protein N-terminal | 341 / 485 | 70.3% | 80.1% of 426 | ≥50% support |
| GO | GO:0016020 Cellular Component | membrane | 359 / 485 | 74.0% | 84.5% of 425 | ≥50% support |
| GO | GO:0005216 Molecular Function | monoatomic ion channel activity | 358 / 485 | 73.8% | 84.2% of 425 | ≥50% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 358 / 485 | 73.8% | 84.2% of 425 | ≥50% support |
| GO | GO:0055085 Biological Process | transmembrane transport | 358 / 485 | 73.8% | 84.2% of 425 | ≥50% support |
| KEGG | K04955 | HCN2 — Ion channels | 295 / 485 | 60.8% | 97.4% of 303 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000012143.1 | XP_028411787.1 | potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2-like [Dendronephthya gigantea] | O88703 Potassium/sodium hyperpolarization-activated cyclic nucleoti | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000012153.1 | XP_028411787.1 | potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2-like [Dendronephthya gigantea] | O88703 Potassium/sodium hyperpolarization-activated cyclic nucleoti | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000024148.1 | XP_046845024.1 | potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1-like [Xenia sp. Carnegie-2017] | Q9UL51 Potassium/sodium hyperpolarization-activated cyclic nucleoti | JBrowse |
