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This orthogroup contains 453 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 453 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF07714 | PK_Tyr_Ser-Thr — Protein tyrosine and serine/threonine kinase | 363 / 453 | 80.1% | 87.7% of 414 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 380 / 453 | 83.9% | 92.0% of 413 | ≥80% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 366 / 453 | 80.8% | 88.6% of 413 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 364 / 453 | 80.4% | 88.1% of 413 | ≥80% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 364 / 453 | 80.4% | 88.1% of 413 | ≥80% support |
| PANTHER | PTHR24416 | TYROSINE-PROTEIN KINASE RECEPTOR | 344 / 453 | 75.9% | 86.0% of 400 | ≥50% support |
| Pfam | PF01392 | Fz | 346 / 453 | 76.4% | 83.6% of 414 | ≥50% support |
| Pfam | PF00051 | Kringle | 310 / 453 | 68.4% | 74.9% of 414 | ≥50% support |
| Pfam | PF07679 | I-set | 295 / 453 | 65.1% | 71.3% of 414 | ≥50% support |
| GO | GO:0004714 Molecular Function | transmembrane receptor protein tyrosine kinase activity | 342 / 453 | 75.5% | 82.8% of 413 | ≥50% support |
| GO | GO:0043235 Cellular Component | receptor complex | 342 / 453 | 75.5% | 82.8% of 413 | ≥50% support |
| GO | GO:0033674 Biological Process | positive regulation of kinase activity | 342 / 453 | 75.5% | 82.8% of 413 | ≥50% support |
| GO | GO:0007275 Biological Process | multicellular organism development | 342 / 453 | 75.5% | 82.8% of 413 | ≥50% support |
| GO | GO:0007169 Biological Process | cell surface receptor protein tyrosine kinase signaling pathway | 342 / 453 | 75.5% | 82.8% of 413 | ≥50% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 342 / 453 | 75.5% | 82.8% of 413 | ≥50% support |
| GO | GO:0014068 Biological Process | obsolete positive regulation of phosphatidylinositol 3-kinase signaling | 333 / 453 | 73.5% | 80.6% of 413 | ≥50% support |
| GO | GO:0010976 Biological Process | positive regulation of neuron projection development | 333 / 453 | 73.5% | 80.6% of 413 | ≥50% support |
| GO | GO:0017147 Molecular Function | Wnt-protein binding | 327 / 453 | 72.2% | 79.2% of 413 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000022829.1 | CAB4009423.1 | inactive tyrosine- kinase transmembrane receptor ROR1-like [Paramuricea clavata] | Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 OS=Homo | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000022839.1 | CAB4009423.1 | inactive tyrosine- kinase transmembrane receptor ROR1-like [Paramuricea clavata] | Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 OS=Homo | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000024447.1 | CAB3985443.1 | inactive tyrosine- kinase transmembrane receptor ROR1-like isoform X1 [Paramuricea clavata] | Q9Z138 Tyrosine-protein kinase transmembrane receptor ROR2 OS=Mus m | JBrowse |
