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This orthogroup contains 450 genes from 133 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 450 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF00531 | Death | 368 / 450 | 81.8% | 90.9% of 405 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 407 / 450 | 90.4% | 100.0% of 407 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 368 / 450 | 81.8% | 90.4% of 407 | ≥80% support |
| PANTHER | PTHR15079 | MYD88 | 324 / 450 | 72.0% | 91.5% of 354 | ≥50% support |
| Pfam | PF13676 | TIR_2 — TIR domain | 317 / 450 | 70.4% | 78.3% of 405 | ≥50% support |
| GO | GO:0002755 Biological Process | MyD88-dependent toll-like receptor signaling pathway | 324 / 450 | 72.0% | 79.6% of 407 | ≥50% support |
| GO | GO:0043123 Biological Process | positive regulation of canonical NF-kappaB signal transduction | 324 / 450 | 72.0% | 79.6% of 407 | ≥50% support |
| GO | GO:0070976 Molecular Function | TIR domain binding | 324 / 450 | 72.0% | 79.6% of 407 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000019494.1 | XP_046862911.1 | myeloid differentiation primary response protein MyD88-like [Xenia sp. Carnegie-2017] | A8QMS7 Myeloid differentiation primary response protein MyD88 OS=Ta | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000019499.1 | XP_028391225.1 | myeloid differentiation primary response protein MyD88-like [Dendronephthya gigantea] | A8QMS7 Myeloid differentiation primary response protein MyD88 OS=Ta | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000019510.1 | XP_028391225.1 | myeloid differentiation primary response protein MyD88-like [Dendronephthya gigantea] | A8QMS7 Myeloid differentiation primary response protein MyD88 OS=Ta | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000039359.1 | XP_046862911.1 | myeloid differentiation primary response protein MyD88-like [Xenia sp. Carnegie-2017] | A8QMS7 Myeloid differentiation primary response protein MyD88 OS=Ta | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000039363.1 | XP_028391225.1 | myeloid differentiation primary response protein MyD88-like [Dendronephthya gigantea] | A8QMS7 Myeloid differentiation primary response protein MyD88 OS=Ta | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000039369.1 | XP_028391225.1 | myeloid differentiation primary response protein MyD88-like [Dendronephthya gigantea] | A8QMS7 Myeloid differentiation primary response protein MyD88 OS=Ta | JBrowse |
