Gene Family

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Member genes
443
Species
145
Sequences
443
Best annotation support
91.4%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 91.4% of the 443 members.

Support counts the member genes carrying the term. % of genes is that count over all 443 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR11164GLUTAMATE CYSTEINE LIGASE405 / 44391.4%99.8%
of 406
≥80% support
PfamPF03074GCS — Glutamate-cysteine ligase380 / 44385.8%99.5%
of 382
≥80% support
GOGO:0004357
Molecular Function
glutamate-cysteine ligase activity406 / 44391.7%100.0%
of 406
≥80% support
GOGO:0006750
Biological Process
glutathione biosynthetic process406 / 44391.7%100.0%
of 406
≥80% support
GOGO:0017109
Cellular Component
glutamate-cysteine ligase complex401 / 44390.5%98.8%
of 406
≥80% support
GOGO:0003824
Molecular Function
catalytic activity368 / 44383.1%90.6%
of 406
≥80% support
KEGGK11204GCLC — Longevity regulating pathway - worm279 / 44363.0%99.3%
of 281
≥50% support
📊 Total members in OG0001816: 2 (filtered to LSARM · show all species)
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Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Leptogorgia sarmentosaENSAPQP00000010572.1CAB4004497.1Glutamate--cysteine ligase catalytic subunit [Paramuricea clavata]P97494
Glutamate--cysteine ligase catalytic subunit OS=Mus musculus
JBrowse
Leptogorgia sarmentosaENSAPQP00000010584.1CAB4004497.1Glutamate--cysteine ligase catalytic subunit [Paramuricea clavata]P48506
Glutamate--cysteine ligase catalytic subunit OS=Homo sapiens
JBrowse
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