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This orthogroup contains 362 genes from 146 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 362 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF00102 | Y_phosphatase — Protein-tyrosine phosphatase | 295 / 362 | 81.5% | 92.8% of 318 | ≥80% support |
| GO | GO:0006470 Biological Process | protein dephosphorylation | 310 / 362 | 85.6% | 97.8% of 317 | ≥80% support |
| GO | GO:0004726 Molecular Function | non-membrane spanning protein tyrosine phosphatase activity | 304 / 362 | 84.0% | 95.9% of 317 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 304 / 362 | 84.0% | 95.9% of 317 | ≥80% support |
| GO | GO:0004725 Molecular Function | protein tyrosine phosphatase activity | 297 / 362 | 82.0% | 93.7% of 317 | ≥80% support |
| PANTHER | PTHR46559 | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 | 203 / 362 | 56.1% | 64.2% of 316 | ≥50% support |
| Pfam | PF00017 | SH2 | 272 / 362 | 75.1% | 85.5% of 318 | ≥50% support |
| GO | GO:0016311 Biological Process | dephosphorylation | 273 / 362 | 75.4% | 86.1% of 317 | ≥50% support |
| GO | GO:0030971 Molecular Function | receptor tyrosine kinase binding | 205 / 362 | 56.6% | 64.7% of 317 | ≥50% support |
| GO | GO:0050839 Molecular Function | cell adhesion molecule binding | 203 / 362 | 56.1% | 64.0% of 317 | ≥50% support |
| GO | GO:0070374 Biological Process | positive regulation of ERK1 and ERK2 cascade | 203 / 362 | 56.1% | 64.0% of 317 | ≥50% support |
| KEGG | K07293 | PTPN11, SHP2 — Protein phosphatases and associated proteins | 220 / 362 | 60.8% | 94.4% of 233 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000005357.1 | CAB4001581.1 | Tyrosine- phosphatase non-receptor type 11 [Paramuricea clavata] | – | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000016536.1 | XP_028393987.1 | tyrosine-protein phosphatase non-receptor type 11-like [Dendronephthya gigantea] | Q90687 Tyrosine-protein phosphatase non-receptor type 11 OS=Gallus | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000034966.1 | XP_028393987.1 | tyrosine-protein phosphatase non-receptor type 11-like [Dendronephthya gigantea] | Q06124 Tyrosine-protein phosphatase non-receptor type 11 OS=Homo sa | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000034979.1 | XP_028393987.1 | tyrosine-protein phosphatase non-receptor type 11-like [Dendronephthya gigantea] | Q90687 Tyrosine-protein phosphatase non-receptor type 11 OS=Gallus | JBrowse |