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This orthogroup contains 356 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 356 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24416 | TYROSINE-PROTEIN KINASE RECEPTOR | 288 / 356 | 80.9% | 91.1% of 316 | ≥80% support |
| Pfam | PF00041 | fn3 — Fibronectin type III domain | 297 / 356 | 83.4% | 93.1% of 319 | ≥80% support |
| Pfam | PF07714 | PK_Tyr_Ser-Thr — Protein tyrosine and serine/threonine kinase | 288 / 356 | 80.9% | 90.3% of 319 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 298 / 356 | 83.7% | 95.2% of 313 | ≥80% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 288 / 356 | 80.9% | 92.0% of 313 | ≥80% support |
| GO | GO:0004714 Molecular Function | transmembrane receptor protein tyrosine kinase activity | 288 / 356 | 80.9% | 92.0% of 313 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 288 / 356 | 80.9% | 92.0% of 313 | ≥80% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 288 / 356 | 80.9% | 92.0% of 313 | ≥80% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 288 / 356 | 80.9% | 92.0% of 313 | ≥80% support |
| GO | GO:0007169 Biological Process | cell surface receptor protein tyrosine kinase signaling pathway | 288 / 356 | 80.9% | 92.0% of 313 | ≥80% support |
| GO | GO:0007275 Biological Process | multicellular organism development | 288 / 356 | 80.9% | 92.0% of 313 | ≥80% support |
| GO | GO:0033674 Biological Process | positive regulation of kinase activity | 288 / 356 | 80.9% | 92.0% of 313 | ≥80% support |
| GO | GO:0043235 Cellular Component | receptor complex | 288 / 356 | 80.9% | 92.0% of 313 | ≥80% support |
| GO | GO:0004713 Molecular Function | protein tyrosine kinase activity | 286 / 356 | 80.3% | 91.4% of 313 | ≥80% support |
| Pfam | PF13927 | Ig_3 — Immunoglobulin domain | 256 / 356 | 71.9% | 80.3% of 319 | ≥50% support |
| Pfam | PF07679 | I-set | 236 / 356 | 66.3% | 74.0% of 319 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000022419.1 | CAB3984345.1 | fibroblast growth factor receptor 4-like isoform X1 [Paramuricea clavata] | Q9VBW3 Tyrosine kinase receptor Cad96Ca OS=Drosophila melanogaster | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000022431.1 | CAB3984345.1 | fibroblast growth factor receptor 4-like isoform X1 [Paramuricea clavata] | Q9VBW3 Tyrosine kinase receptor Cad96Ca OS=Drosophila melanogaster | JBrowse |
