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This orthogroup contains 319 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 319 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | 183 / 319 | 57.4% | 77.5% of 236 | ≥50% support |
| Pfam | PF00618 | RasGEF_N — RasGEF N-terminal motif | 191 / 319 | 59.9% | 82.3% of 232 | ≥50% support |
| Pfam | PF00617 | RasGEF | 177 / 319 | 55.5% | 76.3% of 232 | ≥50% support |
| Pfam | PF00621 | RhoGEF | 173 / 319 | 54.2% | 74.6% of 232 | ≥50% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 239 / 319 | 74.9% | 93.4% of 256 | ≥50% support |
| GO | GO:0007264 Biological Process | small GTPase-mediated signal transduction | 191 / 319 | 59.9% | 74.6% of 256 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 183 / 319 | 57.4% | 71.5% of 256 | ≥50% support |
| GO | GO:0007265 Biological Process | Ras protein signal transduction | 183 / 319 | 57.4% | 71.5% of 256 | ≥50% support |
| GO | GO:0043547 Biological Process | positive regulation of GTPase activity | 183 / 319 | 57.4% | 71.5% of 256 | ≥50% support |
| GO | GO:0046982 Molecular Function | protein heterodimerization activity | 175 / 319 | 54.9% | 68.4% of 256 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000034693.1 | CAB4027132.1 | son of sevenless homolog 1-like [Paramuricea clavata] | Q07889 Son of sevenless homolog 1 OS=Homo sapiens OX=9606 GN=SOS1 P | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000034711.1 | XP_028396040.1 | son of sevenless homolog 1-like [Dendronephthya gigantea] | Q07890 Son of sevenless homolog 2 OS=Homo sapiens OX=9606 GN=SOS2 P | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000034736.1 | XP_028396040.1 | son of sevenless homolog 1-like [Dendronephthya gigantea] | Q07890 Son of sevenless homolog 2 OS=Homo sapiens OX=9606 GN=SOS2 P | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000034778.1 | XP_028396040.1 | son of sevenless homolog 1-like [Dendronephthya gigantea] | Q07890 Son of sevenless homolog 2 OS=Homo sapiens OX=9606 GN=SOS2 P | JBrowse |
