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This orthogroup contains 284 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 284 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR14017 | LYSINE-SPECIFIC DEMETHYLASE | 251 / 284 | 88.4% | 100.0% of 251 | ≥80% support |
| GO | GO:0000978 Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 251 / 284 | 88.4% | 99.2% of 253 | ≥80% support |
| GO | GO:0010468 Biological Process | regulation of gene expression | 251 / 284 | 88.4% | 99.2% of 253 | ≥80% support |
| GO | GO:0031490 Molecular Function | chromatin DNA binding | 251 / 284 | 88.4% | 99.2% of 253 | ≥80% support |
| GO | GO:0044666 Cellular Component | MLL3/4 complex | 251 / 284 | 88.4% | 99.2% of 253 | ≥80% support |
| Pfam | PF02373 | JmjC | 205 / 284 | 72.2% | 84.7% of 242 | ≥50% support |
| Pfam | PF21322 | KDM6_C-hel — Lysine-specific demethylase 6/UTY, C-terminal helical domain | 202 / 284 | 71.1% | 83.5% of 242 | ≥50% support |
| Pfam | PF21326 | KDM6_GATAL — KDM6, GATA-like | 196 / 284 | 69.0% | 81.0% of 242 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 216 / 284 | 76.1% | 85.4% of 253 | ≥50% support |
| KEGG | K11447 | UTX, KDM6A — Chromosome and associated proteins | 174 / 284 | 61.3% | 94.1% of 185 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000029856.1 | XP_028401680.1 | lysine-specific demethylase 6A-like isoform X2 [Dendronephthya gigantea] | O15550 Lysine-specific demethylase 6A OS=Homo sapiens OX=9606 GN=KD | JBrowse |
