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This orthogroup contains 271 genes from 135 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 271 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR46378 | STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN | 232 / 271 | 85.6% | 100.0% of 232 | ≥80% support |
| GO | GO:0000139 Cellular Component | Golgi membrane | 232 / 271 | 85.6% | 97.9% of 237 | ≥80% support |
| GO | GO:0005789 Cellular Component | endoplasmic reticulum membrane | 232 / 271 | 85.6% | 97.9% of 237 | ≥80% support |
| GO | GO:0032933 Biological Process | SREBP signaling pathway | 232 / 271 | 85.6% | 97.9% of 237 | ≥80% support |
| GO | GO:0032934 Molecular Function | sterol binding | 232 / 271 | 85.6% | 97.9% of 237 | ≥80% support |
| GO | GO:0032936 Cellular Component | SREBP-SCAP complex | 232 / 271 | 85.6% | 97.9% of 237 | ≥80% support |
| GO | GO:0045540 Biological Process | regulation of cholesterol biosynthetic process | 232 / 271 | 85.6% | 97.9% of 237 | ≥80% support |
| Pfam | PF12349 | Sterol-sensing | 194 / 271 | 71.6% | 90.7% of 214 | ≥50% support |
| Pfam | PF00400 | WD40 — WD domain, G-beta repeat | 150 / 271 | 55.4% | 70.1% of 214 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 197 / 271 | 72.7% | 83.1% of 237 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000019435.1 | XP_028415687.1 | LOW QUALITY PROTEIN: sterol regulatory element-binding protein cleavage-activating protein-like [Dendronephthya gigantea] | Q12770 Sterol regulatory element-binding protein cleavage-activatin | JBrowse |
