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This orthogroup contains 250 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 250 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45808 | RHO GTPASE-ACTIVATING PROTEIN 68F | 190 / 250 | 76.0% | 93.6% of 203 | ≥50% support |
| Pfam | PF13716 | CRAL_TRIO_2 — Divergent CRAL/TRIO domain | 195 / 250 | 78.0% | 92.4% of 211 | ≥50% support |
| Pfam | PF00620 | RhoGAP | 194 / 250 | 77.6% | 91.9% of 211 | ≥50% support |
| GO | GO:0005096 Molecular Function | GTPase activator activity | 195 / 250 | 78.0% | 99.5% of 196 | ≥50% support |
| GO | GO:0007165 Biological Process | signal transduction | 195 / 250 | 78.0% | 99.5% of 196 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 190 / 250 | 76.0% | 96.9% of 196 | ≥50% support |
| GO | GO:0007264 Biological Process | small GTPase-mediated signal transduction | 190 / 250 | 76.0% | 96.9% of 196 | ≥50% support |
| GO | GO:2001136 Biological Process | negative regulation of endocytic recycling | 188 / 250 | 75.2% | 95.9% of 196 | ≥50% support |
| KEGG | K18470 | ARHGAP1, CDC42GAP — Membrane trafficking | 131 / 250 | 52.4% | 91.6% of 143 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000030518.1 | XP_028397347.1 | rho GTPase-activating protein 8-like isoform X1 [Dendronephthya gigantea] | P85298 Rho GTPase-activating protein 8 OS=Homo sapiens OX=9606 GN=A | JBrowse |