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This orthogroup contains 231 genes from 133 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 231 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13206 | UBIQUITIN LIGASE PROTEIN PHF9 FANCONI ANEMIA GROUP L PROTEIN | 199 / 231 | 86.2% | 100.0% of 199 | ≥80% support |
| GO | GO:0004842 Molecular Function | ubiquitin-protein transferase activity | 199 / 231 | 86.2% | 100.0% of 199 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 199 / 231 | 86.2% | 100.0% of 199 | ≥80% support |
| GO | GO:0006281 Biological Process | DNA repair | 199 / 231 | 86.2% | 100.0% of 199 | ≥80% support |
| GO | GO:0006513 Biological Process | protein monoubiquitination | 199 / 231 | 86.2% | 100.0% of 199 | ≥80% support |
| GO | GO:0036297 Biological Process | interstrand cross-link repair | 199 / 231 | 86.2% | 100.0% of 199 | ≥80% support |
| GO | GO:0043240 Cellular Component | Fanconi anaemia nuclear complex | 199 / 231 | 86.2% | 100.0% of 199 | ≥80% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 199 / 231 | 86.2% | 100.0% of 199 | ≥80% support |
| Pfam | PF18891 | FANCL_d3 — FANCL UBC-like domain 3 | 180 / 231 | 77.9% | 88.7% of 203 | ≥50% support |
| Pfam | PF09765 | FANCL_d1 — FANCL UBC-like domain 1 | 172 / 231 | 74.5% | 84.7% of 203 | ≥50% support |
| Pfam | PF18890 | FANCL_d2 — FANCL UBC-like domain 2 | 168 / 231 | 72.7% | 82.8% of 203 | ≥50% support |
| Pfam | PF11793 | FANCL_C — FANCL C-terminal domain | 166 / 231 | 71.9% | 81.8% of 203 | ≥50% support |
| KEGG | K10606 | FANCL, PHF9 — DNA repair and recombination proteins | 155 / 231 | 67.1% | 99.4% of 156 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000031481.1 | CAB4010538.1 | E3 ubiquitin- ligase FANCL isoform X1 [Paramuricea clavata] | Q9NW38 E3 ubiquitin-protein ligase FANCL OS=Homo sapiens OX=9606 GN | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000031491.1 | CAB4010538.1 | E3 ubiquitin- ligase FANCL isoform X1 [Paramuricea clavata] | Q9NW38 E3 ubiquitin-protein ligase FANCL OS=Homo sapiens OX=9606 GN | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000031500.1 | CAB4010538.1 | E3 ubiquitin- ligase FANCL isoform X1 [Paramuricea clavata] | Q9NW38 E3 ubiquitin-protein ligase FANCL OS=Homo sapiens OX=9606 GN | JBrowse |
