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This orthogroup contains 198 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 198 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13040 | AUTOPHAGY PROTEIN 5 | 172 / 198 | 86.9% | 99.4% of 173 | ≥80% support |
| Pfam | PF20637 | ATG5_HBR — Autophagy protein ATG5, alpha-helical bundle region | 164 / 198 | 82.8% | 93.2% of 176 | ≥80% support |
| Pfam | PF20638 | ATG5_UblA — Autophagy protein ATG5, UblA domain | 164 / 198 | 82.8% | 93.2% of 176 | ≥80% support |
| Pfam | PF04106 | ATG5_UblB — Autophagy protein ATG5, UblB domain | 160 / 198 | 80.8% | 90.9% of 176 | ≥80% support |
| GO | GO:0000045 Biological Process | autophagosome assembly | 172 / 198 | 86.9% | 99.4% of 173 | ≥80% support |
| GO | GO:0000422 Biological Process | autophagy of mitochondrion | 172 / 198 | 86.9% | 99.4% of 173 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 172 / 198 | 86.9% | 99.4% of 173 | ≥80% support |
| GO | GO:0006501 Biological Process | C-terminal protein lipidation | 172 / 198 | 86.9% | 99.4% of 173 | ≥80% support |
| GO | GO:0006914 Biological Process | autophagy | 172 / 198 | 86.9% | 99.4% of 173 | ≥80% support |
| GO | GO:0006995 Biological Process | cellular response to nitrogen starvation | 172 / 198 | 86.9% | 99.4% of 173 | ≥80% support |
| GO | GO:0019776 Molecular Function | Atg8-family ligase activity | 172 / 198 | 86.9% | 99.4% of 173 | ≥80% support |
| GO | GO:0034045 Cellular Component | phagophore assembly site membrane | 172 / 198 | 86.9% | 99.4% of 173 | ≥80% support |
| GO | GO:0034274 Cellular Component | Atg12-Atg5-Atg16 complex | 172 / 198 | 86.9% | 99.4% of 173 | ≥80% support |
| GO | GO:0044804 Biological Process | nucleophagy | 172 / 198 | 86.9% | 99.4% of 173 | ≥80% support |
| KEGG | K08339 | ATG5 — Mitochondrial biogenesis | 161 / 198 | 81.3% | 99.4% of 162 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000001629.1 | CAB4024159.1 | autophagy 5-like [Paramuricea clavata] | Q3MQ24 Autophagy protein 5 OS=Bos taurus OX=9913 GN=ATG5 PE=2 SV=2 | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000001642.1 | CAB4024159.1 | autophagy 5-like [Paramuricea clavata] | Q3MQ24 Autophagy protein 5 OS=Bos taurus OX=9913 GN=ATG5 PE=2 SV=2 | JBrowse |
