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This orthogroup contains 191 genes from 138 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 191 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13703 | SMAD | 173 / 191 | 90.6% | 100.0% of 173 | ≥80% support |
| Pfam | PF03166 | MH2 | 168 / 191 | 88.0% | 97.1% of 173 | ≥80% support |
| GO | GO:0006355 Biological Process | regulation of DNA-templated transcription | 173 / 191 | 90.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0006357 Biological Process | regulation of transcription by RNA polymerase II | 173 / 191 | 90.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0007179 Biological Process | transforming growth factor beta receptor signaling pathway | 173 / 191 | 90.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0009653 Biological Process | anatomical structure morphogenesis | 173 / 191 | 90.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0030154 Biological Process | cell differentiation | 173 / 191 | 90.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0060395 Biological Process | SMAD protein signal transduction | 173 / 191 | 90.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0070411 Molecular Function | I-SMAD binding | 173 / 191 | 90.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0071144 Cellular Component | heteromeric SMAD protein complex | 173 / 191 | 90.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0140416 Molecular Function | transcription regulator inhibitor activity | 173 / 191 | 90.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 169 / 191 | 88.5% | 97.7% of 173 | ≥80% support |
| Pfam | PF03165 | MH1 | 147 / 191 | 77.0% | 85.0% of 173 | ≥50% support |
| GO | GO:0005667 Cellular Component | transcription regulator complex | 150 / 191 | 78.5% | 86.7% of 173 | ≥50% support |
| KEGG | K04677 | SMAD6 — TGF-beta signaling pathway | 109 / 191 | 57.1% | 97.3% of 112 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000031276.1 | CAB4000545.1 | mothers against decapentaplegic homolog 6-like [Paramuricea clavata] | Q1W668 Mothers against decapentaplegic homolog 2 OS=Bos taurus OX=9 | JBrowse |
| Leptogorgia sarmentosa | ENSAPQP00000031285.1 | CAB4000545.1 | mothers against decapentaplegic homolog 6-like [Paramuricea clavata] | Q1W668 Mothers against decapentaplegic homolog 2 OS=Bos taurus OX=9 | JBrowse |
