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This orthogroup contains 162 genes from 132 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 162 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR16231 | COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER | 147 / 162 | 90.7% | 100.0% of 147 | ≥80% support |
| Pfam | PF07258 | COMM_domain — COMM domain | 143 / 162 | 88.3% | 97.3% of 147 | ≥80% support |
| Pfam | PF21672 | COMM_HN — COMMD protein HN domain | 133 / 162 | 82.1% | 90.5% of 147 | ≥80% support |
| GO | GO:0032088 Biological Process | negative regulation of NF-kappaB transcription factor activity | 147 / 162 | 90.7% | 100.0% of 147 | ≥80% support |
| GO | GO:0033209 Biological Process | tumor necrosis factor-mediated signaling pathway | 147 / 162 | 90.7% | 100.0% of 147 | ≥80% support |
| GO | GO:0045892 Biological Process | negative regulation of DNA-templated transcription | 147 / 162 | 90.7% | 100.0% of 147 | ≥80% support |
| GO | GO:0051059 Molecular Function | NF-kappaB binding | 147 / 162 | 90.7% | 100.0% of 147 | ≥80% support |
| KEGG | K22563 | COMMD7 — Ubiquitin system | 119 / 162 | 73.5% | 98.4% of 121 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptogorgia sarmentosa | ENSAPQP00000037773.1 | CAB3977356.1 | Hypothetical predicted protein [Paramuricea clavata] | Q8BG94 COMM domain-containing protein 7 OS=Mus musculus OX=10090 GN | JBrowse |
