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This orthogroup contains 668 genes from 148 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 668 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11835 | DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE | 574 / 668 | 85.9% | 97.3% of 590 | ≥80% support |
| Pfam | PF00180 | Iso_dh — Isocitrate/isopropylmalate dehydrogenase | 584 / 668 | 87.4% | 100.0% of 584 | ≥80% support |
| GO | GO:0006099 Biological Process | tricarboxylic acid cycle | 579 / 668 | 86.7% | 98.1% of 590 | ≥80% support |
| GO | GO:0006102 Biological Process | isocitrate metabolic process | 574 / 668 | 85.9% | 97.3% of 590 | ≥80% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 563 / 668 | 84.3% | 95.4% of 590 | ≥80% support |
| GO | GO:0016616 Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 531 / 668 | 79.5% | 90.0% of 590 | ≥50% support |
| GO | GO:0051287 Molecular Function | NAD binding | 531 / 668 | 79.5% | 90.0% of 590 | ≥50% support |
| GO | GO:0000287 Molecular Function | magnesium ion binding | 530 / 668 | 79.3% | 89.8% of 590 | ≥50% support |
| KEGG | K00030 | IDH3 — Citrate cycle (TCA cycle) | 500 / 668 | 74.9% | 96.3% of 519 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptoseris scabra | ANN00544-RA | CAH3193566.1 | unnamed protein product, partial [Porites evermanni] | Q9D6R2 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial | JBrowse |
| Leptoseris scabra | ANN04013-RA | XP_029191641.2 | isocitrate dehydrogenase [NAD] subunit beta, mitochondrial-like [Acropora millepora] | Q28479 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial O | JBrowse |
| Leptoseris scabra | ANN22610-RA | XP_020612083.1 | isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial-like [Orbicella faveolata] | P41565 Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondria | JBrowse |
