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Support counts the member genes carrying the term. % of genes is that count over all 556 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45655 | GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 | 490 / 556 | 88.1% | 96.7% of 507 | ≥80% support |
| Pfam | PF07701 | HNOBA — Heme NO binding associated | 483 / 556 | 86.9% | 95.1% of 508 | ≥80% support |
| Pfam | PF00211 | Guanylate_cyc — Adenylate and Guanylate cyclase catalytic domain | 475 / 556 | 85.4% | 93.5% of 508 | ≥80% support |
| GO | GO:0004383 Molecular Function | guanylate cyclase activity | 508 / 556 | 91.4% | 100.0% of 508 | ≥80% support |
| GO | GO:0006182 Biological Process | cGMP biosynthetic process | 497 / 556 | 89.4% | 97.8% of 508 | ≥80% support |
| GO | GO:0008074 Cellular Component | guanylate cyclase complex, soluble | 490 / 556 | 88.1% | 96.5% of 508 | ≥80% support |
| GO | GO:0019934 Biological Process | cGMP-mediated signaling | 490 / 556 | 88.1% | 96.5% of 508 | ≥80% support |
| GO | GO:0038060 Biological Process | nitric oxide-cGMP-mediated signaling | 490 / 556 | 88.1% | 96.5% of 508 | ≥80% support |
| GO | GO:0070482 Biological Process | response to oxygen levels | 490 / 556 | 88.1% | 96.5% of 508 | ≥80% support |
| GO | GO:0035556 Biological Process | intracellular signal transduction | 476 / 556 | 85.6% | 93.7% of 508 | ≥80% support |
| GO | GO:0009190 Biological Process | cyclic nucleotide biosynthetic process | 475 / 556 | 85.4% | 93.5% of 508 | ≥80% support |
| Pfam | PF07700 | HNOB — Haem-NO-binding | 420 / 556 | 75.5% | 82.7% of 508 | ≥50% support |
| GO | GO:0020037 Molecular Function | heme binding | 420 / 556 | 75.5% | 82.7% of 508 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptoseris scabra | ANN07503-RA | CAH3161392.1 | unnamed protein product [Porites lobata] | Q8INF0 Soluble guanylate cyclase 88E OS=Drosophila melanogaster OX= | JBrowse |
| Leptoseris scabra | ANN07512-RA | XP_015765307.1 | PREDICTED: soluble guanylate cyclase 88E-like [Acropora digitifera] | Q8INF0 Soluble guanylate cyclase 88E OS=Drosophila melanogaster OX= | JBrowse |
| Leptoseris scabra | ANN18135-RA | CAH3131152.1 | unnamed protein product [Porites lobata] | Q8INF0 Soluble guanylate cyclase 88E OS=Drosophila melanogaster OX= | JBrowse |