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This orthogroup contains 337 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 337 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11773 | GLYCINE DEHYDROGENASE, DECARBOXYLATING | 296 / 337 | 87.8% | 99.3% of 298 | ≥80% support |
| Pfam | PF02347 | GDC-P — Glycine cleavage system P-protein | 270 / 337 | 80.1% | 91.5% of 295 | ≥80% support |
| GO | GO:0004375 Molecular Function | glycine dehydrogenase (decarboxylating) activity | 297 / 337 | 88.1% | 99.7% of 298 | ≥80% support |
| GO | GO:0005960 Cellular Component | glycine cleavage complex | 296 / 337 | 87.8% | 99.3% of 298 | ≥80% support |
| GO | GO:0006546 Biological Process | glycine catabolic process | 296 / 337 | 87.8% | 99.3% of 298 | ≥80% support |
| GO | GO:0016594 Molecular Function | glycine binding | 296 / 337 | 87.8% | 99.3% of 298 | ≥80% support |
| GO | GO:0019464 Biological Process | glycine decarboxylation via glycine cleavage system | 296 / 337 | 87.8% | 99.3% of 298 | ≥80% support |
| GO | GO:0030170 Molecular Function | pyridoxal phosphate binding | 296 / 337 | 87.8% | 99.3% of 298 | ≥80% support |
| Pfam | PF21478 | GcvP2_C — Glycine dehydrogenase, C-terminal domain | 239 / 337 | 70.9% | 81.0% of 295 | ≥50% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 243 / 337 | 72.1% | 81.5% of 298 | ≥50% support |
| GO | GO:0006544 Biological Process | glycine metabolic process | 197 / 337 | 58.5% | 66.1% of 298 | ≥50% support |
| KEGG | K00281 | GLDC, gcvP — Lipoic acid metabolism | 221 / 337 | 65.6% | 95.3% of 232 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptoseris scabra | ANN28683-RA | CAH3172502.1 | unnamed protein product [Porites evermanni] | Q91W43 Glycine dehydrogenase (decarboxylating), mitochondrial OS=Mu | JBrowse |
