Gene Family

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🧬 OG0003337

This orthogroup contains 295 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 76.6%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 295 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PfamPF12796Ank_2 — Ankyrin repeats (3 copies)226 / 29576.6%88.3%
of 256
≥50% support
PfamPF00008EGF206 / 29569.8%80.5%
of 256
≥50% support
PfamPF12661hEGF — Human growth factor-like EGF186 / 29563.1%72.7%
of 256
≥50% support
PfamPF00066Notch — LNR domain180 / 29561.0%70.3%
of 256
≥50% support
PfamPF07645EGF_CA — Calcium-binding EGF domain175 / 29559.3%68.4%
of 256
≥50% support
PfamPF07684NODP — NOTCH protein172 / 29558.3%67.2%
of 256
≥50% support
PfamPF06816NOD — NOTCH protein166 / 29556.3%64.8%
of 256
≥50% support
GOGO:0005515
Molecular Function
protein binding227 / 29577.0%88.7%
of 256
≥50% support
GOGO:0005509
Molecular Function
calcium ion binding208 / 29570.5%81.3%
of 256
≥50% support
GOGO:0007219
Biological Process
Notch signaling pathway201 / 29568.1%78.5%
of 256
≥50% support
GOGO:0016020
Cellular Component
membrane197 / 29566.8%77.0%
of 256
≥50% support
GOGO:0030154
Biological Process
cell differentiation197 / 29566.8%77.0%
of 256
≥50% support
GOGO:0007275
Biological Process
multicellular organism development173 / 29558.6%67.6%
of 256
≥50% support
GOGO:0050793
Biological Process
regulation of developmental process149 / 29550.5%58.2%
of 256
≥50% support
KEGGK02599NOTCH1 — Endocrine resistance152 / 29551.5%96.8%
of 157
≥50% support
📊 Total members in OG0003337: 1 (filtered to LSCAB · show all species)
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Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Leptoseris scabraANN00706-RAXP_029197633.2LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1-like [Acropora millepora]Q04721
Neurogenic locus notch homolog protein 2 OS=Homo sapiens OX=
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