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This orthogroup contains 265 genes from 80 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 265 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR14453 | PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN | 225 / 265 | 84.9% | 98.7% of 228 | ≥80% support |
| Pfam | PF01661 | Macro | 213 / 265 | 80.4% | 93.0% of 229 | ≥80% support |
| GO | GO:0003950 Molecular Function | NAD+-protein poly-ADP-ribosyltransferase activity | 225 / 265 | 84.9% | 92.2% of 244 | ≥80% support |
| GO | GO:0003714 Molecular Function | transcription corepressor activity | 224 / 265 | 84.5% | 91.8% of 244 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 224 / 265 | 84.5% | 91.8% of 244 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 224 / 265 | 84.5% | 91.8% of 244 | ≥80% support |
| GO | GO:0010629 Biological Process | negative regulation of gene expression | 224 / 265 | 84.5% | 91.8% of 244 | ≥80% support |
| GO | GO:0070212 Biological Process | protein poly-ADP-ribosylation | 224 / 265 | 84.5% | 91.8% of 244 | ≥80% support |
| GO | GO:0140289 Biological Process | obsolete protein mono-ADP-ribosylation | 224 / 265 | 84.5% | 91.8% of 244 | ≥80% support |
| GO | GO:1990404 Molecular Function | NAD+-protein ADP-ribosyltransferase activity | 224 / 265 | 84.5% | 91.8% of 244 | ≥80% support |
| Pfam | PF00644 | PARP — Poly(ADP-ribose) polymerase catalytic domain | 182 / 265 | 68.7% | 79.5% of 229 | ≥50% support |
| GO | GO:0003676 Molecular Function | nucleic acid binding | 184 / 265 | 69.4% | 75.4% of 244 | ≥50% support |
| GO | GO:0003723 Molecular Function | RNA binding | 171 / 265 | 64.5% | 70.1% of 244 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptoseris scabra | ANN31951-RA | PFX17028.1 | Poly [ADP-ribose] polymerase 14 [Stylophora pistillata] | Q8BZ20 Protein mono-ADP-ribosyltransferase PARP12 OS=Mus musculus O | JBrowse |
| Leptoseris scabra | ANN31953-RA | CAH3113542.1 | unnamed protein product [Porites lobata] | Q9ZBG3 Macro domain-containing protein SCO6450 OS=Streptomyces coel | JBrowse |
| Leptoseris scabra | ANN34690-RA | XP_027041202.1 | poly [ADP-ribose] polymerase 14-like isoform X1 [Pocillopora damicornis] | Q8BZ20 Protein mono-ADP-ribosyltransferase PARP12 OS=Mus musculus O | JBrowse |
| Leptoseris scabra | ANN34697-RA | CAH3113540.1 | unnamed protein product [Porites lobata] | Q2EMV9 Protein mono-ADP-ribosyltransferase PARP14 OS=Mus musculus O | JBrowse |
| Leptoseris scabra | ANN34699-RA | CAH3113542.1 | unnamed protein product [Porites lobata] | B4T2X8 O-acetyl-ADP-ribose deacetylase OS=Salmonella newport (strai | JBrowse |