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This orthogroup contains 264 genes from 109 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 264 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | 175 / 264 | 66.3% | 76.4% of 229 | ≥50% support |
| Pfam | PF00617 | RasGEF | 176 / 264 | 66.7% | 76.2% of 231 | ≥50% support |
| Pfam | PF00027 | cNMP_binding — Cyclic nucleotide-binding domain | 134 / 264 | 50.8% | 58.0% of 231 | ≥50% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 179 / 264 | 67.8% | 80.6% of 222 | ≥50% support |
| GO | GO:0007264 Biological Process | small GTPase-mediated signal transduction | 179 / 264 | 67.8% | 80.6% of 222 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 175 / 264 | 66.3% | 78.8% of 222 | ≥50% support |
| GO | GO:0007265 Biological Process | Ras protein signal transduction | 175 / 264 | 66.3% | 78.8% of 222 | ≥50% support |
| GO | GO:0043547 Biological Process | positive regulation of GTPase activity | 175 / 264 | 66.3% | 78.8% of 222 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptoseris scabra | ANN13334-RA | CAH3140228.1 | unnamed protein product [Porites lobata] | Q8WZA2 Rap guanine nucleotide exchange factor 4 OS=Homo sapiens OX= | JBrowse |
| Leptoseris scabra | ANN13336-RA | CAH3140228.1 | unnamed protein product [Porites lobata] | Q9Z1C7 Rap guanine nucleotide exchange factor 4 (Fragment) OS=Rattu | JBrowse |
