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This orthogroup contains 255 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 255 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11811 | 6-PHOSPHOGLUCONATE DEHYDROGENASE | 225 / 255 | 88.2% | 99.6% of 226 | ≥80% support |
| Pfam | PF00393 | 6PGD — 6-phosphogluconate dehydrogenase, C-terminal domain | 221 / 255 | 86.7% | 97.8% of 226 | ≥80% support |
| Pfam | PF03446 | NAD_binding_2 — NAD binding domain of 6-phosphogluconate dehydrogenase | 208 / 255 | 81.6% | 92.0% of 226 | ≥80% support |
| GO | GO:0004616 Molecular Function | phosphogluconate dehydrogenase (decarboxylating) activity | 226 / 255 | 88.6% | 100.0% of 226 | ≥80% support |
| GO | GO:0050661 Molecular Function | NADP binding | 224 / 255 | 87.8% | 99.1% of 226 | ≥80% support |
| GO | GO:0005829 Cellular Component | cytosol | 222 / 255 | 87.1% | 98.2% of 226 | ≥80% support |
| GO | GO:0009051 Biological Process | pentose-phosphate shunt, oxidative branch | 222 / 255 | 87.1% | 98.2% of 226 | ≥80% support |
| GO | GO:0046177 Biological Process | D-gluconate catabolic process | 222 / 255 | 87.1% | 98.2% of 226 | ≥80% support |
| GO | GO:0006098 Biological Process | pentose-phosphate shunt | 221 / 255 | 86.7% | 97.8% of 226 | ≥80% support |
| KEGG | K00033 | PGD, gnd, gntZ — Glutathione metabolism | 197 / 255 | 77.3% | 100.0% of 197 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptoseris scabra | ANN11365-RA | XP_020621917.1 | 6-phosphogluconate dehydrogenase, decarboxylating-like [Orbicella faveolata] | P52209 6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sa | JBrowse |
