Gene Family

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🧬 OG0005258

This orthogroup contains 239 genes from 136 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 85.8%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 239 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PfamPF10174Cast — RIM-binding protein of the cytomatrix active zone205 / 23985.8%98.6%
of 208
≥80% support
PANTHERPTHR18861ELKS/RAB6-INTERACTING/CAST PROTEIN173 / 23972.4%92.5%
of 187
≥50% support
GOGO:0007274
Biological Process
neuromuscular synaptic transmission173 / 23972.4%96.7%
of 179
≥50% support
GOGO:0048167
Biological Process
regulation of synaptic plasticity173 / 23972.4%96.7%
of 179
≥50% support
GOGO:0048788
Cellular Component
cytoskeleton of presynaptic active zone173 / 23972.4%96.7%
of 179
≥50% support
GOGO:0048790
Biological Process
maintenance of presynaptic active zone structure173 / 23972.4%96.7%
of 179
≥50% support
GOGO:0098882
Molecular Function
structural constituent of presynaptic active zone173 / 23972.4%96.7%
of 179
≥50% support
📊 Total members in OG0005258: 1 (filtered to LSCAB · show all species)
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Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Leptoseris scabraANN23367-RAXP_029203230.2LOW QUALITY PROTEIN: ELKS/Rab6-interacting/CAST family member 1-like [Acropora millepora]O15083
ERC protein 2 OS=Homo sapiens OX=9606 GN=ERC2 PE=1 SV=3
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